Rohrschneider K, Becker M, Schumacher N, Fendrich T, Völcker H E
Department of Ophthalmology, University of Heidelberg, Germany.
Am J Ophthalmol. 1998 Jul;126(1):52-8. doi: 10.1016/s0002-9394(98)00065-8.
To evaluate the normal light sensitivity values for fundus perimetry and their short time fluctuation (reliability) in normal volunteers of different ages. After the development of full-threshold static fundus perimetry, age-corrected sensitivity values for normal subjects are required to interpret results and to compare them with conventional computerized perimetry.
Full-threshold fundus perimetry of the central field (33 x 21 degrees) by means of the scanning laser ophthalmoscope was performed on 152 eyes of 99 healthy persons aged 16 to 77 years with normal vision and no eye disease. Fixation was simultaneously documented. Light sensitivity values were evaluated according to each subject's age and test point location.
Linear regression analysis disclosed a significant (P < .0001) decrease of the mean sensitivity of 0.275 dB per decade of increasing age, starting with 16.6 dB at age 10 years. Standard deviation around the center of fixation was 0.287 degrees in the first decade, and it increased by 2.82 minutes of arc per decade (P < .0001). Variation in triple examinations of subjects did not differ from short time fluctuation.
Visual fields examined with fundus perimetry show reliable measurements in a range comparable to conventional computerized perimetry. There is a significant correlation between increase of age and decrease of light sensitivity in fundus perimetry. Visual fields obtained with fundus perimetry seem to correlate well with known data from computerized static threshold perimetry. It should be recognized that even in normal subjects, the stability of fixation decreases with increasing age.
评估不同年龄正常志愿者眼底视野计的正常光敏感度值及其短时间波动(可靠性)。在全阈值静态眼底视野计发展之后,需要正常受试者的年龄校正敏感度值来解释结果并与传统电脑视野计进行比较。
使用扫描激光检眼镜对99名年龄在16至77岁、视力正常且无眼部疾病的健康人进行152只眼的中央视野(33×21度)全阈值眼底视野计检查。同时记录注视情况。根据每个受试者的年龄和测试点位置评估光敏感度值。
线性回归分析显示,平均敏感度随年龄每增加十岁显著降低(P <.0001),10岁时为16.6 dB,此后每十年降低0.275 dB。注视中心周围的标准差在第一个十年为0.287度,此后每十年增加2.82分弧度(P <.0001)。受试者三次检查的差异与短时间波动无差异。
眼底视野计检查的视野在与传统电脑视野计相当的范围内显示出可靠的测量结果。年龄增加与眼底视野计光敏感度降低之间存在显著相关性。眼底视野计获得的视野似乎与电脑静态阈值视野计的已知数据相关性良好。应该认识到,即使在正常受试者中,注视稳定性也会随着年龄的增加而降低。