Isen K, Küpeli B, Sinik Z, Sözen S, Bozkirli I
Department of Urology, Gazi University, Faculty of Medicine, Ankara, Turkey.
Int Urol Nephrol. 1999;31(4):491-5. doi: 10.1023/a:1007115312039.
We investigated the efficacy of prophylactic use of single dose oral ofloxacin and trimethoprim-sulfamethoxazole regimens for transrectal prostate biopsy in 110 men. In the ofloxacin, trimethoprim-sulfamethoxazole and control groups, urinary infection was found in 2 (4.76%), 3 (6.66%) and 6 (26.08%) patients, respectively. Both of these antibiotic regimens produced a statistically significant reduction in urinary infection (p<0.02, p<0.05). Our study indicates that single dose fluoroquinolone or trimethoprim-sulfamethoxazole prophylaxis seems to be effective, practical and economical.
我们研究了110名男性经直肠前列腺活检时单剂量口服氧氟沙星及甲氧苄啶-磺胺甲恶唑预防性用药方案的疗效。在氧氟沙星组、甲氧苄啶-磺胺甲恶唑组和对照组中，分别有2例（4.76%）、3例（6.66%）和6例（26.08%）患者发生泌尿系统感染。这两种抗生素方案均使泌尿系统感染率出现具有统计学意义的降低（p<0.02，p<0.05）。我们的研究表明，单剂量氟喹诺酮类药物或甲氧苄啶-磺胺甲恶唑预防用药似乎有效、实用且经济。
