Thylstrup A, Poulsen S
Community Dent Oral Epidemiol. 1976 Sep;4(5):200-4. doi: 10.1111/j.1600-0528.1976.tb00984.x.
The aim of the present study was to evaluate the retention and effectiveness of a bis-GMA type of fissure sealant which polymerizes after conventional mixing of the two catalyst/activator components (Concise Enamel Bond System). Unilateral sealing of homologous pairs of permanent first molars was carried out by a dental hygienist. Of the 451 sealed sites sealant was present in 73%, partly missing in 8%, and completely missing in 18% after 1 year. The effectiveness of the treatment in preventing occlusal caries was highly significant and the caries reduction was found to be about 70%. A strong relationship between status of sealant and occlusal decay was demonstrated. The shortcomings of the half-mouth design when evaluating sealants as a caries-preventive measure in public dental health programs are discussed.
本研究的目的是评估一种双甲基丙烯酸缩水甘油酯型窝沟封闭剂的保留率和有效性，该封闭剂在两种催化剂/活化剂组分常规混合后聚合（简明牙釉质粘结系统）。一名牙科保健员对恒牙第一磨牙的同源对进行单侧封闭。1年后，在451个封闭部位中，73%的部位封闭剂存在，8%的部位部分缺失，18%的部位完全缺失。该治疗在预防咬合面龋齿方面的有效性非常显著，龋齿减少率约为70%。封闭剂状态与咬合面龋坏之间存在密切关系。讨论了在公共牙科保健项目中评估封闭剂作为一种防龋措施时半口设计的缺点。
