Paun M, Beach K, Ahmad S, Hickman R, Meissner M, Plett C, Strandness D E
Department of Surgery, Division of Vascular Surgery, University of Washington School of Medicine, Seattle, WA 98195-6410, USA.
Am J Kidney Dis. 2000 Mar;35(3):477-81. doi: 10.1016/s0272-6386(00)70201-0.
The failure of dialysis access is a frequent source of morbidity and hospitalization. Traditional methods of graft surveillance include: (1) clinical examination, (2) venous line pressure measurements during dialysis, (3) urea or tracer recirculation measurement, (4) continuous wave (CW) Doppler methods, (5) duplex ultrasonography, and (6) radiograph angiography. All these methods require special training and/or laboratory tests. The purpose of this study was to test a simple continuous-wave Doppler method that could be applied to measure the flow rate in dialysis access every time the patient undergoes dialysis. Twenty dialysis patients, 15 with polytetrafluoroethylene grafts and 5 with arteriovenous fistulae, were studied. Two hundred fifty-three examinations were performed over an 8-month period. Doppler waveforms of the access flow were obtained with the pump on, with the pump off, and with the pump on again. Systolic and diastolic Doppler frequency measurements were made, and the pump-on and pump-off measurements were compared. In an access functioning normally, the Doppler frequencies are higher with the pump off than with the pump on. In 22% of the cases, there were abnormal findings in which the Doppler frequencies were lower with the pump off than with the pump on. This occurs if the needles are incorrectly placed, suggesting that recirculation is occurring. Recirculation also occurs if there is stenosis of the access. Examining the hemodialysis access during each dialysis session with an inexpensive directional Doppler may identify a significant stenosis and improve the efficiency of dialysis by detecting those patients in whom the arterial and venous needles are reversed.
透析通路失功是发病和住院的常见原因。传统的移植物监测方法包括:(1)临床检查;(2)透析期间静脉管路压力测量;(3)尿素或示踪剂再循环测量;(4)连续波(CW)多普勒方法;(5)双功超声检查;(6)血管造影X线片。所有这些方法都需要特殊培训和/或实验室检测。本研究的目的是测试一种简单的连续波多普勒方法,该方法可在患者每次进行透析时用于测量透析通路的血流量。对20例透析患者进行了研究,其中15例使用聚四氟乙烯移植物,5例使用动静脉内瘘。在8个月的时间内进行了253次检查。分别在血泵运转时、血泵停止时以及血泵再次运转时获取通路血流的多普勒波形。进行收缩期和舒张期多普勒频率测量,并比较血泵运转时和血泵停止时的测量结果。在功能正常的通路中,血泵停止时的多普勒频率高于血泵运转时。在22%的病例中,发现了异常情况,即血泵停止时的多普勒频率低于血泵运转时。如果穿刺针放置不当就会出现这种情况,提示发生了再循环。如果通路存在狭窄,也会发生再循环。在每次透析过程中使用廉价的定向多普勒检查血液透析通路,可能会发现明显的狭窄,并通过检测出动脉针和静脉针位置颠倒的患者来提高透析效率。