Meier A, Baum M
Acta Anaesthesiol Scand Suppl. 1976;63:1-20.
The occurrence of intrapulmonary redistribution "pendelluft" during the plateau phase of a respirator, with and without internal compliance, was studied in a lung-model which simulated an obstructive inhomogeneity. Internal compliance was achieved by adding a flask, with a variable volume, to the patient circuit of a respirator which had a low compressible volume (Engström Care System ECS 2000, Junger Instrument AB, Sweden). The amount of redistributed volume was found to be dependent upon the internal compliance. Without additional compressible volume, the ventilator produced up to 18% redistribution which under all conditions could be brought below the 1% level when an internal compliance was introduced. A highly significant correlation between the amount of redistributed volume (pendelluft) and the discharge time-constant of the plateau (taupl = CI (RI + Rtr) could be established. The results of mathematical consideration gained from an electrical analogue coincided with our experimental findings. From this, some consequences could be derived for the design of an internal compliance for use with a respirator.
在模拟阻塞性不均匀性的肺模型中,研究了在呼吸机平台期有或无内部顺应性情况下肺内再分布“摆动气”的发生情况。通过在具有低可压缩容积的呼吸机患者回路中添加一个容积可变的烧瓶来实现内部顺应性(瑞典荣格仪器公司的恩斯特朗护理系统ECS 2000)。发现再分布容积的量取决于内部顺应性。在没有额外可压缩容积的情况下,呼吸机产生高达18%的再分布,而当引入内部顺应性时,在所有条件下都可将其降至1%以下。可以确定再分布容积(摆动气)的量与平台期排出时间常数(taupl = CI (RI + Rtr))之间存在高度显著的相关性。从电模拟得出的数学考虑结果与我们的实验结果一致。由此,可以得出一些关于与呼吸机一起使用的内部顺应性设计的结论。