Kapadia S B, Kaplan S S
Cancer. 1976 Dec;38(6):2557-60. doi: 10.1002/1097-0142(197612)38:6<2557::aid-cncr2820380646>3.0.co;2-u.
The simultaneous occurrence of nodular poorly differentiated lymphocytic lymphoma (NLPD) and acute myelomonocytic leukemia (AMML) was confirmed by the histologic examination of lymph node section, peripheral blood, and bone marrow. This association in the absence of previous chemotherapy or radiotherapy has not been previously documented. There have been six previous case reports of patients with non-Hodgkin's lymphocytic lymphoma who, during treatment with alkylating agents or radiotherapy, developed acute myeloid leukemia (AML). These methods of therapy may have had a leukemogenic role in such patients. The possible relationship between these two diseases is discussed.
通过对淋巴结切片、外周血和骨髓进行组织学检查，证实了结节性低分化淋巴细胞淋巴瘤（NLPD）和急性粒单核细胞白血病（AMML）同时存在。这种在未进行过化疗或放疗情况下的关联此前尚未见报道。之前有六例非霍奇金淋巴细胞淋巴瘤患者在接受烷化剂治疗或放疗期间发生急性髓系白血病（AML）的病例报告。这些治疗方法可能在此类患者中起到了致白血病的作用。本文讨论了这两种疾病之间可能的关系。
