Youness E, Ahearn M J, Drewinko B
Am J Clin Pathol. 1978 Sep;70(3):415-20. doi: 10.1093/ajcp/70.3.415.
The diagnosis of non-Hodgkin's lymphoma with spontaneous acute granulocytic leukemia was confirmed by examination of the patient's bone marrow and peripheral blood specimens at the light and electron microscopic level, and by autopsy findings. Only one previous case of simultaneous non-Hodgkin's lymphoma and acute myelomonocytic leukemia with no prior history of chemotherapy, radiotherapy, or both, has been reported. Although the present patient was given no mutagenic therapy, his chronic exposure to an unknown insecticide may have played a leukemogenic role.
通过对患者骨髓和外周血标本进行光镜及电镜检查，并结合尸检结果，确诊为非霍奇金淋巴瘤合并自发性急性粒细胞白血病。此前仅报道过一例同时患有非霍奇金淋巴瘤和急性粒单核细胞白血病且无化疗、放疗或两者联合治疗史的病例。尽管该患者未接受诱变治疗，但其长期接触一种未知杀虫剂可能起到了致白血病的作用。
