Johnson B A, Nunley J R
Medical College of Virginia Campus of Virginia Commonwealth University, Richmond 23298-0230, USA.
Postgrad Med. 2000 Mar;107(3):69-70, 73-6, 79-80. doi: 10.3810/pgm.2000.03.945.
Although management of acne is sometimes difficult, primary care physicians can offer a number of treatment plans to patients with this skin condition. Comedonal acne usually responds to topical keratolytics, such as salicylic acid, benzoyl peroxide, adapalene, and tretinoin. Inflammatory acne is usually treated with topical therapy plus a systemic antibiotic. Nodulocystic acne generally requires an 8-week course of systemic antibiotics. If the nodulocystic acne does not improve, minocycline or isotretinoin may be needed. Topical therapy is often helpful in the long-term management of nodulocystic acne. New products are available that deliver topical agents in novel ways that decrease skin irritation. With the proper tools and instructions in use, most patients have significant improvement in their acne.
虽然痤疮的治疗有时颇具难度，但基层医疗医生可为患有这种皮肤疾病的患者提供多种治疗方案。粉刺性痤疮通常对局部角质溶解剂有反应，如水杨酸、过氧化苯甲酰、阿达帕林和维甲酸。炎性痤疮通常采用局部治疗加全身性抗生素进行治疗。结节囊肿性痤疮一般需要8周的全身性抗生素疗程。如果结节囊肿性痤疮没有改善，可能需要使用米诺环素或异维甲酸。局部治疗在结节囊肿性痤疮的长期管理中通常很有帮助。有一些新产品能够以减少皮肤刺激的新颖方式递送局部用药。有了合适的工具和使用说明，大多数患者的痤疮都有显著改善。
