Taylor R C, Harris N A, Singleton E G, Moolchan E T, Heishman S J
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA.
Exp Clin Psychopharmacol. 2000 Feb;8(1):75-87. doi: 10.1037//1064-1297.8.1.75.
Two experiments were conducted to determine whether active imagery would elicit tobacco craving in smokers with histories of drug abuse who were not interested in quitting smoking. In Experiment 1, the authors used scripts that contained positive, negative, or neutral affective content with and without descriptions of smoking urge. Scripts with urge content and negative affect scripts increased subjective reports of tobacco craving. An interaction between affective manipulation and urge content was observed on self-reported mood. In Experiment 2, positive affect scripts that varied in amount of urge content produced an orderly increase in tobacco craving as a function of urge intensity, suggesting that changes were specific to the imagery manipulation. In both experiments, increases in tobacco craving were positively correlated with craving for drug of choice, suggesting that stimuli that engender smoking urges may occasion craving for other drugs of abuse.
