Schalén C, Christensen P
Acta Pathol Microbiol Scand C. 1979 Feb;87C(1):37-40.
Antibodies to streptococcal peptidoglycan (PG) were detected by gel-precipitation in 38% of sera from blood donors and in 71% of sera with a Waaler-Rose test titre of greater than or equal to 1:64. Twenty-six rheumatoid arthritis sera revealed patterns of interference with complete or partial fusion between PG and aggregated human IgG while none of the sera precipitating both these preparations showed non-interference. The reactions were interpreted as denoting interference between the PG-antibody complexes and aggregated IgG. Conversion of some non-precipitating blood donor sera to PG precipitation was obtained by addition of isolated rheumatoid factor, in itself not precipitating PG, to the sera. Thus, the high frequency of PG precipitation among rheumatoid arthritis sera could--at least in part--be attributed to the participation of anti-IgG in the reaction.
通过凝胶沉淀法在38%的献血者血清以及71%瓦勒-罗斯试验效价大于或等于1:64的血清中检测到了抗链球菌肽聚糖（PG）抗体。26份类风湿性关节炎血清显示出对PG与聚集的人IgG之间完全或部分融合的干扰模式，而沉淀这两种制剂的血清均未显示无干扰情况。这些反应被解释为表明PG - 抗体复合物与聚集的IgG之间存在干扰。通过向血清中添加本身不沉淀PG的分离类风湿因子，可使一些不沉淀的献血者血清转化为PG沉淀。因此，类风湿性关节炎血清中PG沉淀的高频率至少部分可归因于抗IgG参与了反应。
