Schachenmayr W, Heymer B, Haferkamp O
Z Immunitatsforsch Exp Klin Immunol. 1975 Jul;149(2-4):179-86.
A recently described latex agglutination test was used to determine peptidoglycan antibody titers in sera from healthy human subjects and in sera from patients with a history of streptococcal infections or rheumatoid arthritis. Using latex particles coated with group A streptococcal peptidoglycan 32.8% of the sera from 961 healthy donors reacted positively with titers ranging from 1 : 5 to 1 : 320. Peptidoglycan antibodies were more frequently present in the younger population (45.1% in the 20-29 years old) and considerably decreased in advanced age (15.7% in the 70 years or older). Sera from 82 patients with elevated ASO-titers showed detectable peptidoglycan antibody levels in 40.2%; a statistically significant correlation between ASO and peptidoglycan antibody titers could not be substantiated. Sera from 25 patients with rheumatoid arthritis gave a high incidence (56-92%) of positive results. However there was evidence that this may be due to the action of rheumatoid factor present in such sera.
采用最近描述的乳胶凝集试验来测定健康人血清以及有链球菌感染史或类风湿关节炎患者血清中的肽聚糖抗体滴度。使用包被有A组链球菌肽聚糖的乳胶颗粒，961名健康献血者中有32.8%的血清呈阳性反应，滴度范围为1:5至1:320。肽聚糖抗体在较年轻人群中更常见（20 - 29岁人群中为45.1%），而在高龄人群中显著减少（70岁及以上人群中为15.7%）。82名抗链球菌溶血素O（ASO）滴度升高患者的血清中，40.2%检测到肽聚糖抗体水平；ASO与肽聚糖抗体滴度之间无统计学意义上的显著相关性。25名类风湿关节炎患者的血清阳性结果发生率较高（56 - 92%）。然而，有证据表明这可能是由于此类血清中存在类风湿因子的作用。
