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[足月妊娠健康女性母乳及其他组织中的滴滴涕及相关农药]

[DDT and related pesticides in maternal milk and other tissues of healthy women at term pregnancy].

作者信息

Terrones M C, Llamas J, Jaramillo F, Espino M G, León J S

出版信息

Ginecol Obstet Mex. 2000 Mar;68:97-104.

Abstract

Ten healthy patients with term pregnancy resolved by abdominal via. During the surgical procedure samples of umbilical chord serum and maternal adipose tissue, were taken. In all the samples, together with the maternal milk collected the day 10 of puerperium, the concentrations of the following organochlorine pesticides, were measured up: (PCC); beta-BHC; gamma-BHC; heptachloride; aldrin; dieldrin, DDE, DDD, DDT and methoxychloride. The identification and quantification of pesticides was done by the comparison with standards certified by NIST (National Institute of Standard Technology). The general characteristics of the participants were: primigestas of 24.1 years aged, married and of a low socioeconomical level. As to the neonates, of 39 weeks of gestational age, female sex; 3,311 g of corporal weight and size of 51.1 cm. In all the analyzed samples at least one of the organochlorine pesticides was present. The results of correlation analysis between DDT concentration, present in the maternal serum with those identified in the adipose tissue and serum from the umbilical chord were highly significant: a = 0.97 and 0.87, respectively. In the maternal milk the highest concentrations of total DDT, were found, average of 2053 ng/g lipidic base, which is 2.8 times more of daily accepted intake. Likewise, DDT concentration in maternal serum kept exponential relation, growing with age (a = 0.99).

摘要

10名足月妊娠的健康患者经腹部途径分娩。手术过程中采集了脐带血清和母体脂肪组织样本。在所有样本中,连同产后第10天收集的母乳一起,测定了以下有机氯农药的浓度:(PCC);β-六六六;γ-六六六;七氯;艾氏剂;狄氏剂、滴滴伊、滴滴滴、滴滴涕和甲氧滴滴涕。通过与美国国家标准与技术研究院(NIST)认证的标准进行比较来鉴定和定量农药。参与者的一般特征为:年龄24.1岁的初产妇,已婚,社会经济水平较低。至于新生儿,胎龄39周,女性;体重3311克,身长51.1厘米。在所有分析样本中,至少存在一种有机氯农药。母体血清中存在的滴滴涕浓度与脂肪组织和脐带血清中鉴定出的滴滴涕浓度之间的相关性分析结果非常显著:分别为a = 0.97和0.87。母乳中总滴滴涕的浓度最高平均为2053纳克/克脂质基,是每日可接受摄入量的2.8倍。同样,母体血清中滴滴涕浓度与年龄呈指数关系,随年龄增长(a = 0.99)。

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