Waliszewski S M, Aguirre A A, Infanzon R M, Silva C S, Siliceo J
Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, Boca de Río, Ver. C.P. 94290, Mexico.
Arch Environ Contam Toxicol. 2001 Apr;40(3):432-8. doi: 10.1007/s002440010194.
Organochlorine pesticides, due to their persistence, accumulate in food chains and cause elevated contamination in human beings. These residues bioconcentrate in lipid-rich tissues according to the equilibrium pattern of internal transport and lipid tissue content. The analyses of maternal adipose tissue, maternal blood serum, umbilical blood serum, colostrum, and mature milk indicate circulation of these compounds through all compartments of the maternal body, including their crossover of the placental barrier. The greatest residue levels found correspond to DDTs, with highest levels determined in colostrum (5.71 mg/kg of DDT total), followed by adipose tissue with 5.66 mg/kg and in mature milk with 4.70 mg/kg. Among DDTs, pp'DDE is the most predominant compound. The paired analyses of organochlorine pesticide residue levels between mother blood serum and umbilical blood serum demonstrate significant correlation and their transfer from mother to fetus through the placenta. The paired analyses of adipose tissue and colostrum and mature milk contamination levels indicate a high degree of coherence, principally of DDT, in the body and lactation as a decontamination means.
有机氯农药由于其持久性，会在食物链中累积，并导致人体污染加剧。这些残留物根据内部运输和脂质组织含量的平衡模式，在富含脂质的组织中进行生物浓缩。对母体脂肪组织、母体血清、脐血血清、初乳和成熟乳的分析表明，这些化合物在母体身体的所有部分循环，包括穿过胎盘屏障。所发现的最高残留水平对应于滴滴涕，初乳中的含量最高（总滴滴涕为5.71毫克/千克），其次是脂肪组织，含量为5.66毫克/千克，成熟乳中为4.70毫克/千克。在滴滴涕中，对，对'-滴滴伊是最主要的化合物。对母体血清和脐血血清中有机氯农药残留水平的配对分析表明存在显著相关性，且它们通过胎盘从母体转移到胎儿。对脂肪组织与初乳和成熟乳污染水平的配对分析表明，在体内以及作为一种去污方式的哺乳期，主要是滴滴涕，存在高度一致性。
