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利用恢复期血清检测23种免疫原性肺炎球菌蛋白。

Detection of 23 immunogenic pneumococcal proteins using convalescent-phase serum.

作者信息

Zysk G, Bongaerts R J, ten Thoren E, Bethe G, Hakenbeck R, Heinz H P

机构信息

Department of Medical Microbiology and Virology, University of Duesseldorf, Duesseldorf, Germany.

出版信息

Infect Immun. 2000 Jun;68(6):3740-3. doi: 10.1128/IAI.68.6.3740-3743.2000.

Abstract

A genomic expression library of Streptococcus pneumoniae was screened with a convalescent-phase serum for immunoreactive proteins. Six known and 17 unknown pneumococcal proteins were detected. Five of the known proteins were surface-located virulence factors, and eight of the unknown proteins were putative membrane proteins.

摘要

用恢复期血清筛选肺炎链球菌的基因组表达文库以寻找免疫反应性蛋白。检测到6种已知和17种未知的肺炎球菌蛋白。其中5种已知蛋白是位于表面的毒力因子,8种未知蛋白是推定的膜蛋白。

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