Kozarić-Kovacić D, Ljubin T, Grappe M
National Center for Psychotrauma, University Hospital Dubrava, Zagreb, Croatia.
Croat Med J. 2000 Jun;41(2):173-8.
To investigate in displaced persons a) the prevalence rate of current posttraumatic stress disorder (PTSD) and alcohol dependence; b) the relationship of alcohol dependence and current PTSD; and c) trauma exposure in relation to alcohol dependence comorbid to PTSD.
A group of displaced persons (157 men and 211 women) was interviewed using structured clinical interview based on DSM-III-R criteria for diagnosing PTSD and alcohol dependence, Watson's PTSD Questionnaire, and CAGE Questionnaire.
Men showed higher prevalence rate of a current PTSD (50.3% of men vs. 36.5% of women, p=0.011), alcohol dependence (60.5% of men vs. 8.1% of women, p<0. 001), and alcohol dependence comorbid with PTSD (69.6% of men vs. 11. 7% of women, p<0.001). The rate of alcohol dependence increased in relation to current PTSD in men but not in women. Comorbidity of alcohol dependence and PTSD in women was influenced by alcohol-related problems before the war, whereas in men it was not influenced by any of the pre-war variables. The highest number of traumas was experienced by the displaced persons with a current PTSD only, followed by those with PTSD and alcohol dependence. The lowest number of war traumas was experienced by displaced persons with alcohol dependence, but without current PTSD.
War traumas may have a role in the development of alcohol dependence in displaced men with current PTSD. The number of war traumas had a strong effect on the development of PTSD. Sex is a relevant factor in studying comorbidity of current PTSD and alcohol dependence.
调查流离失所者中：a）当前创伤后应激障碍（PTSD）和酒精依赖的患病率；b）酒精依赖与当前PTSD的关系；c）与PTSD共病的酒精依赖相关的创伤暴露情况。
使用基于DSM-III-R标准的结构化临床访谈对一组流离失所者（157名男性和211名女性）进行访谈，以诊断PTSD和酒精依赖、使用沃森PTSD问卷及CAGE问卷。
男性当前PTSD的患病率更高（男性为50.3%，女性为36.5%，p = 0.011），酒精依赖患病率更高（男性为60.5%，女性为8.1%，p < 0.001），与PTSD共病的酒精依赖患病率更高（男性为69.6%，女性为11.7%，p < 0.001）。男性中酒精依赖率随当前PTSD的出现而增加，女性则不然。女性中酒精依赖与PTSD的共病受战前与酒精相关问题的影响，而男性则不受任何战前变量的影响。仅患有当前PTSD的流离失所者经历的创伤数量最多，其次是患有PTSD和酒精依赖的人。患有酒精依赖但无当前PTSD的流离失所者经历的战争创伤数量最少。
战争创伤可能在患有当前PTSD的流离失所男性酒精依赖的发展中起作用。战争创伤的数量对PTSD的发展有很大影响。性别是研究当前PTSD与酒精依赖共病的一个相关因素。
