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锐药木的植物化学、药理学及毒性研究综述

Phytochemistry, pharmacology and toxicity of Rhazya stricta decne: a review.

作者信息

Ali B H, Al-Qarawi A A, Bashir A K, Tanira M O

机构信息

Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Buraydah, Al Gaseem, Saudi Arabia.

出版信息

Phytother Res. 2000 Jun;14(4):229-34. doi: 10.1002/1099-1573(200006)14:4<229::aid-ptr673>3.0.co;2-5.

DOI:10.1002/1099-1573(200006)14:4<229::aid-ptr673>3.0.co;2-5
PMID:10861963
Abstract

Phytochemical, pharmacological and toxicological properties of the medicinal plant Rhazya stricta Decne. are reviewed. Several types of alkaloids and a few flavonoids have been isolated and their structures and stereochemistry characterized. However, in most cases the biological activity of these compounds has not been studied. Most of the pharmacological activity of the plant resides in its alkaloidal fractions which cause depression of the central nervous system and hypotension. Extracts of R. stricta appear to have low toxicity, although its use in pregnant women may be inadvisable.

摘要

对药用植物沙漠玫瑰(Rhazya stricta Decne.)的植物化学、药理学和毒理学特性进行了综述。已分离出几种生物碱和一些黄酮类化合物,并对其结构和立体化学进行了表征。然而,在大多数情况下,这些化合物的生物活性尚未得到研究。该植物的大部分药理活性存在于其生物碱部分,会导致中枢神经系统抑制和低血压。沙漠玫瑰提取物似乎毒性较低,尽管不建议孕妇使用。

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