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美国老年人群失明和视力损害的原因:索尔兹伯里眼评估研究

Causes of blindness and visual impairment in a population of older Americans: The Salisbury Eye Evaluation Study.

作者信息

Muñoz B, West S K, Rubin G S, Schein O D, Quigley H A, Bressler S B, Bandeen-Roche K

机构信息

Wilmer Eye Institute, The Johns Hopkins University, 600 N Wolfe St, Room 116, Baltimore, MD 21287, USA.

出版信息

Arch Ophthalmol. 2000 Jun;118(6):819-25. doi: 10.1001/archopht.118.6.819.

Abstract

OBJECTIVE

To determine the causes of blindness and visual impairment in a population-based sample of older Americans.

METHODS

A random sample of 3821 residents of Salisbury, Md, between the ages of 65 and 84 years was identified from Medicare records. Sixty-six percent (2520 persons) agreed to undergo an eye examination; 26% of the participants were African American. The clinical examination included acuity testing with an Early Treatment Diabetic Retinopathy Study chart and standardized refraction testing for those with a visual acuity worse than 20/30, slitlamp and dilated retinal examination by an ophthalmologist, tonometry, lens and fundus photography, and a suprathreshold visual field test. Visual impairment was defined as a best-corrected acuity in the better-seeing eye worse than 20/40 and better than 20/200, while blindness was acuity in the better-seeing eye of 20/200 or worse. For those with a visual acuity worse than 20/40 in either eye, one or more causes were assigned by an ophthalmologist and a final cause for each eye was confirmed by a panel of 3 subspecialty ophthalmologists (O.D.S., H.A.Q., and S.B.B.) based on all available evidence.

RESULTS

Bilateral presenting acuity worse than 20/40 increased from 4% in the 65- to 74-year age group to 16% in the 80- to 84-year age group. One third of those with presenting acuity worse than 20/40 improved to 20/40 or better with refraction. Overall, 4.5% had a best-corrected acuity worse than 20/40. African Americans were more likely to remain visually impaired than were whites despite refraction (odds ratio [95% confidence interval], 1.7 [1.1-2.6]). Whites were most often impaired or blind from age-related macular degeneration (1.2% vs 0.5%; P=.09). African Americans had higher rates of impairment and blindness from cataract or posterior capsular opacification (2.7% vs 1.1%; P=.006), glaucoma (0.9% vs 0.1%; P=.006), and diabetic retinopathy (1.2% vs 0.2%; P=. 004).

CONCLUSIONS

More than half of those with visual impairment or blindness had conditions that were either surgically treatable or potentially preventable. African Americans had a disproportionate number of blinding diseases, particularly those amenable to eye care intervention. Targeted interventions for specific populations to increase appropriate eye care use would greatly improve vision and function in older Americans. Arch Ophthalmol. 2000;118:819-825

摘要

目的

确定以美国老年人群为基础样本中失明和视力损害的原因。

方法

从医疗保险记录中识别出马里兰州索尔兹伯里市3821名年龄在65至84岁之间的居民随机样本。66%(2520人)同意接受眼部检查;26%的参与者为非裔美国人。临床检查包括使用糖尿病视网膜病变早期治疗研究图表进行视力测试,以及为视力低于20/30的患者进行标准化验光测试,由眼科医生进行裂隙灯和散瞳视网膜检查、眼压测量、晶状体和眼底摄影,以及超阈值视野测试。视力损害定义为较好眼的最佳矫正视力低于20/40且优于20/200,而失明则是较好眼的视力为20/200或更差。对于任何一只眼视力低于20/40的患者,由一名眼科医生确定一种或多种病因,并由3名眼科亚专科医生(O.D.S.、H.A.Q.和S.B.B.)组成的小组根据所有可用证据确认每只眼的最终病因。

结果

双眼初始视力低于20/40的比例从65至74岁年龄组的4%增加到80至84岁年龄组的16%。初始视力低于20/40的患者中有三分之一通过验光后视力提高到20/40或更好。总体而言,4.5%的患者最佳矫正视力低于20/40。尽管进行了验光,非裔美国人比白人更有可能保持视力损害(优势比[95%置信区间],1.7[1.1 - 2.6])。白人最常因年龄相关性黄斑变性而视力受损或失明(1.2%对0.5%;P = 0.09)。非裔美国人因白内障或后囊膜混浊、青光眼和糖尿病视网膜病变导致的视力损害和失明发生率更高(2.7%对1.1%;P = 0.006),(0.9%对0.1%;P = 0.006),(1.2%对0.2%;P = 0.004)。

结论

超过一半的视力损害或失明患者患有可通过手术治疗或可能预防的疾病。非裔美国人患有致盲疾病的比例过高,尤其是那些适合眼部护理干预的疾病。针对特定人群的有针对性干预措施,以增加适当的眼部护理使用,将极大地改善美国老年人的视力和功能。《眼科学文献》。2000年;118:819 - 825

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