酿酒酵母中的尿素转运
Urea transport in Saccharomyces cerevisiae.
作者信息
Cooper T G, Sumrada R
出版信息
J Bacteriol. 1975 Feb;121(2):571-6. doi: 10.1128/jb.121.2.571-576.1975.
Abstract
Urea transport in Saccharomyces cerevisiae occurs by two pathways. The first mode of uptake is via an active transport system which: (i) has an apparent Km value of 14 muM, (ii) is absolutely dependent upon energy metabolism, (iii) requires pre-growth of the cultures in the presence of oxaluric acid, gratuitous inducer of the allantoin degradative enzymes, and (iv) is sensitive to nitrogen repression. The second mode of uptake which occurs at external urea concentrations in excess of 0.5 mM is via either passive or facilitated diffusion.
摘要
酿酒酵母中的尿素转运通过两条途径进行。第一种摄取模式是通过一个主动转运系统，该系统：(i) 表观 Km 值为 14 μM，(ii) 绝对依赖于能量代谢，(iii) 需要在草尿酸（尿囊素降解酶的 gratuitous 诱导剂）存在的情况下对培养物进行预培养，以及 (iv) 对氮阻遏敏感。第二种摄取模式发生在外部尿素浓度超过 0.5 mM 时，是通过被动扩散或易化扩散。
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