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相似文献

1
Urea transport in Saccharomyces cerevisiae.酿酒酵母中的尿素转运
J Bacteriol. 1975 Feb;121(2):571-6. doi: 10.1128/jb.121.2.571-576.1975.
2
Urea transport-defective strains of Saccharomyces cerevisiae.酿酒酵母尿素转运缺陷型菌株。
J Bacteriol. 1976 Mar;125(3):1048-56. doi: 10.1128/jb.125.3.1048-1056.1976.
3
Oxaluric acid: a non-metabolizable inducer of the allantoin degradative enzymes in Saccharomyces cerevisiae.草尿酸：酿酒酵母中尿囊素降解酶的一种不可代谢诱导剂。
J Bacteriol. 1974 Mar;117(3):1240-7. doi: 10.1128/jb.117.3.1240-1247.1974.
4
Allantoin transport in Saccharomyces cerevisiae.酿酒酵母中的尿囊素转运
J Bacteriol. 1977 Sep;131(3):839-47. doi: 10.1128/jb.131.3.839-847.1977.
5
Nitrogen repression of the allantoin degradative enzymes in Saccharomyces cerevisiae.酿酒酵母中尿囊素降解酶的氮阻遏作用。
J Bacteriol. 1974 Jun;118(3):821-9. doi: 10.1128/jb.118.3.821-829.1974.
6
Allantoate transport in Saccharomyces cerevisiae.酿酒酵母中的尿囊酸转运
J Bacteriol. 1979 Dec;140(3):971-9. doi: 10.1128/jb.140.3.971-979.1979.
7
Oxalurate transport in Saccharomyces cerevisiae.酿酒酵母中的草尿酸转运
J Bacteriol. 1979 Sep;139(3):917-23. doi: 10.1128/jb.139.3.917-923.1979.
8
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Can J Microbiol. 1974 Aug;20(8):1109-18. doi: 10.1139/m74-173.
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J Bacteriol. 1978 Aug;135(2):490-7. doi: 10.1128/jb.135.2.490-497.1978.
10
The induction of urea carboxylase and allophanate hydrolase in Saccharomyces cerevisiae.
J Biol Chem. 1973 Sep 10;248(17):6203-9.

引用本文的文献

1
Deletion of the N-Terminal Domain of Yeast Eukaryotic Initiation Factor 4B Reprograms Translation and Reduces Growth in Urea.酵母真核起始因子4B N端结构域的缺失重编程翻译并降低在尿素中的生长。
Front Mol Biosci. 2022 Jan 3;8:787781. doi: 10.3389/fmolb.2021.787781. eCollection 2021.
2
Analysis of NH Transport and Central Nitrogen Metabolism in Saccharomyces cerevisiae during Aerobic Nitrogen-Limited Growth.酿酒酵母在有氧氮限制生长期间的氮转运与中心氮代谢分析
Appl Environ Microbiol. 2016 Dec 1;82(23):6831-6845. doi: 10.1128/AEM.01547-16. Epub 2016 Sep 16.
3
Role of nitrogen sources and metal ions in urease synthesis byMicrococcus varians.氮源和金属离子在微球菌变异脲酶合成中的作用。
World J Microbiol Biotechnol. 1990 Jun;6(2):195-200. doi: 10.1007/BF01200941.
4
L-ornithine transaminase synthesis in Saccharomyces cerevisiae: Induction by allophanate, intermediate and inducer of the urea degradative pathway adds to arginine induction.酵母中 L-鸟氨酸转氨酶的合成：别噁氨酸盐的诱导作用，尿素降解途径的中间产物和诱导剂，增加了精氨酸的诱导作用。
Curr Genet. 1981 Sep;4(1):69-72. doi: 10.1007/BF00376788.
5
Positive regulatory elements involved in urea amidolyase and urea uptake induction in Saccharomyces cerevisiae.参与酵母属酿酒酵母中尿素 amidolyase 和尿素摄取诱导的正调控元件。
Curr Genet. 1981 Sep;4(1):13-8. doi: 10.1007/BF00376780.
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Nitrogen source-dependent capsule induction in human-pathogenic cryptococcus species.人类致病隐球菌物种中氮源依赖性荚膜诱导
Eukaryot Cell. 2013 Nov;12(11):1439-50. doi: 10.1128/EC.00169-13. Epub 2013 Aug 23.
7
Molecular mechanisms of urea transport in plants.植物中尿素转运的分子机制。
J Membr Biol. 2006;212(2):83-91. doi: 10.1007/s00232-006-0868-6. Epub 2007 Jan 30.
8
Nitrogen catabolite repression in Saccharomyces cerevisiae.酿酒酵母中的氮代谢物阻遏
Mol Biotechnol. 1999 Aug;12(1):35-73. doi: 10.1385/MB:12:1:35.
9
Regulation of the urea active transporter gene (DUR3) in Saccharomyces cerevisiae.酿酒酵母中尿素活性转运蛋白基因（DUR3）的调控
J Bacteriol. 1993 Aug;175(15):4688-98. doi: 10.1128/jb.175.15.4688-4698.1993.
10
The genetics and biochemistry of urease in Ustilago violacea.紫黑粉菌中脲酶的遗传学与生物化学
Biochem Genet. 1981 Dec;19(11-12):1101-14. doi: 10.1007/BF00484568.

本文引用的文献

1
Amide metabolism in yeasts. II. The uptake of amide and amide like compounds by yeast.
J Biochem. 1962 Sep;52:149-54.
2
Requirement for HCO3- by ATP: urea amido-lyase in yeast.酵母中ATP：尿素酰胺裂解酶对HCO3-的需求
Biochem Biophys Res Commun. 1970 Aug 24;40(4):814-9. doi: 10.1016/0006-291x(70)90975-7.
3
Mechanism of hydrolysis of O-nitrophenyl-beta-galactoside in Staphylococcus aureus and its significance for theories of sugar transport.金黄色葡萄球菌中O-硝基苯基-β-半乳糖苷的水解机制及其对糖转运理论的意义。
Proc Natl Acad Sci U S A. 1967 Jul;58(1):225-8. doi: 10.1073/pnas.58.1.225.
4
Effects of colicins E1 and K on transport systems.大肠杆菌素E1和K对转运系统的影响。
J Bacteriol. 1969 Jan;97(1):57-63. doi: 10.1128/jb.97.1.57-63.1969.
5
Lomofungin, an inhibitor of ribonucleic acid synthesis in yeast protoplasts: its effect on enzyme formation.洛莫真菌素，一种酵母原生质体核糖核酸合成抑制剂：其对酶形成的影响。
Antimicrob Agents Chemother. 1973 Jun;3(6):716-22. doi: 10.1128/AAC.3.6.716.
6
Induction of the allantoin degradative enzymes in Saccharomyces cerevisiae by the last intermediate of the pathway.通过该途径的最后中间体诱导酿酒酵母中的尿囊素降解酶。
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2340-4. doi: 10.1073/pnas.70.8.2340.
7
Nitrogen repression of the allantoin degradative enzymes in Saccharomyces cerevisiae.酿酒酵母中尿囊素降解酶的氮阻遏作用。
J Bacteriol. 1974 Jun;118(3):821-9. doi: 10.1128/jb.118.3.821-829.1974.
8
Oxaluric acid: a non-metabolizable inducer of the allantoin degradative enzymes in Saccharomyces cerevisiae.草尿酸：酿酒酵母中尿囊素降解酶的一种不可代谢诱导剂。
J Bacteriol. 1974 Mar;117(3):1240-7. doi: 10.1128/jb.117.3.1240-1247.1974.
9
Effects of inducer addition and removal upon the level of allophanate hydrolase in Saccharomyces cerevisiae.诱导剂添加和去除对酿酒酵母中脲基甲酸酯水解酶水平的影响。
Biochem Biophys Res Commun. 1973 Dec 19;55(4):1100-4. doi: 10.1016/s0006-291x(73)80008-7.
10
The induction of urea carboxylase and allophanate hydrolase in Saccharomyces cerevisiae.
J Biol Chem. 1973 Sep 10;248(17):6203-9.

酿酒酵母中的尿素转运

Urea transport in Saccharomyces cerevisiae.

作者信息

Cooper T G, Sumrada R

出版信息

J Bacteriol. 1975 Feb;121(2):571-6. doi: 10.1128/jb.121.2.571-576.1975.

DOI:10.1128/jb.121.2.571-576.1975
PMID:1089637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC245968/
Abstract

Urea transport in Saccharomyces cerevisiae occurs by two pathways. The first mode of uptake is via an active transport system which: (i) has an apparent Km value of 14 muM, (ii) is absolutely dependent upon energy metabolism, (iii) requires pre-growth of the cultures in the presence of oxaluric acid, gratuitous inducer of the allantoin degradative enzymes, and (iv) is sensitive to nitrogen repression. The second mode of uptake which occurs at external urea concentrations in excess of 0.5 mM is via either passive or facilitated diffusion.

摘要

酿酒酵母中的尿素转运通过两条途径进行。第一种摄取模式是通过一个主动转运系统，该系统：(i) 表观 Km 值为 14 μM，(ii) 绝对依赖于能量代谢，(iii) 需要在草尿酸（尿囊素降解酶的 gratuitous 诱导剂）存在的情况下对培养物进行预培养，以及 (iv) 对氮阻遏敏感。第二种摄取模式发生在外部尿素浓度超过 0.5 mM 时，是通过被动扩散或易化扩散。