Kalsow C M, Wacker W B
Int Arch Allergy Appl Immunol. 1975;48(2):287-93. doi: 10.1159/000231314.
Three distinct immunofluorescent patterns were demonstrated in normal guinea pig eyes by autoantisera prepared to three different ocular tissue preparations. Anti-U serum (antiserum to ureal homogenate) exhibited specific fluorescence in the area of Bruch's membrane. Anti-P serum (antiserum to a suspension of the sedimentable portion of retina homogenate) exhibited specific fluorescence in the outer segments of the photoreceptor cells. Anti-S serum (antiserum to retinal homogenate extract) demonstrated specific fluorescence in the outer portion of the retina extending from the outer plexiform layer to the outer segments of the photoreceptor cells. The ability of anti-S and anti-P sera immunofluorescent activities to cross species lines was demonstrated.
用针对三种不同眼组织制剂制备的自身抗血清，在正常豚鼠眼中显示出三种不同的免疫荧光模式。抗 - U血清（针对尿素匀浆的抗血清）在布鲁赫膜区域呈现特异性荧光。抗 - P血清（针对视网膜匀浆可沉淀部分悬浮液的抗血清）在光感受器细胞的外段呈现特异性荧光。抗 - S血清（针对视网膜匀浆提取物的抗血清）在从外网状层延伸至光感受器细胞外段的视网膜外层显示出特异性荧光。还证明了抗 - S和抗 - P血清的免疫荧光活性具有跨物种作用的能力。
