Ehresmann C, Stiegler P, Mackie G A, Zimmermann R A, Ebel J P, Fellner P
Nucleic Acids Res. 1975 Feb;2(2):265-78. doi: 10.1093/nar/2.2.265.
Recent progress in the nucleotide sequence analysis of the 16S ribosomal RNA from E. coli is described. The sequence which has been partially or completely determined so far encompasses 1520 nucleotides, i.e. about 95% of the molecule. Possible features of the secondary structure are suggested on the basis of the nucleotide sequence and data on sequence heterogeneities, repetitions and the location of modified nucleotides are presented. In the accompanying paper, the use of the nucleotide sequence data in studies of the ribosomal protein binding sites is described.
本文描述了大肠杆菌16S核糖体RNA核苷酸序列分析的最新进展。目前已部分或完全确定的序列包含1520个核苷酸,约占该分子的95%。根据核苷酸序列提出了二级结构的可能特征,并给出了序列异质性、重复序列和修饰核苷酸位置的数据。在随附的论文中,描述了核苷酸序列数据在核糖体蛋白结合位点研究中的应用。