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溶菌酶对不同抗体类别补体依赖性杀菌作用的影响。

The effect of lysozyme on the complement-dependent bactericidal action of different antibody classes.

作者信息

Heddle R J, Knop J, Steele E J, Rowley D

出版信息

Immunology. 1975 Jun;28(6):1061-6.

PMID:1093969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445890/
Abstract

Preparations of rabbit, dog and sheep IgA, IgA and IgM were examined for their antibacterial effects using a complement-dependent bactericidal assay. IgM and IgG were efficient bactericidal antibodies in the presence of complement; IgA, however, contained negligible activity. Except for sheep IgG no enhancement of bactericidal activity was observed in the presence of added lysozyme.

摘要

利用补体依赖杀菌试验检测了兔、狗和羊的IgA、IgA和IgM制剂的抗菌效果。在有补体存在的情况下，IgM和IgG是有效的杀菌抗体；然而，IgA的活性可忽略不计。除羊IgG外，添加溶菌酶后未观察到杀菌活性增强。

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本文引用的文献

1
Serological Properties of gammaG and gammaM Antibodies to the Somatic Antigen of Vibrio cholerae During the Course of Immunization of Rabbits.在兔体免疫过程中对霍乱弧菌菌体抗原的γG 和 γM 抗体的血清学特性。
Infect Immun. 1971 Jun;3(6):803-9. doi: 10.1128/iai.3.6.803-809.1971.
2
The determination of lysozyme.溶菌酶的测定
J Bacteriol. 1949 Dec;58(6):731-6. doi: 10.1128/jb.58.6.731-736.1949.
3
Development of bactericidal properties against gram-negative organisms in the serum of young animals.幼龄动物血清中针对革兰氏阴性菌的杀菌特性的发展
Folia Microbiol (Praha). 1962 May;7:162-74. doi: 10.1007/BF02928237.
4
The serological specificities of Pasteurella pseudotuberculosis somatic antigens.伪结核耶尔森氏菌菌体抗原的血清学特异性
J Gen Microbiol. 1958 Feb;18(1):129-39. doi: 10.1099/00221287-18-1-129.
5
The virulence of strains of Bacterium coli for mice.大肠杆菌菌株对小鼠的毒力。
Br J Exp Pathol. 1954 Dec;35(6):528-38.
6
Sensitivity of rough gram-negative bacteria to the bactericidal action of serum.粗糙革兰氏阴性菌对血清杀菌作用的敏感性。
J Bacteriol. 1968 May;95(5):1647-50. doi: 10.1128/jb.95.5.1647-1650.1968.
7
The isolation and biologic activities of purified secretory IgA and IgG anti-Salmonella typhimurium "O" antibodies from rabbit intestinal fluid and colostrum.从兔肠道液和初乳中分离纯化分泌型IgA及抗鼠伤寒沙门氏菌“O”抗体IgG并研究其生物学活性
J Immunol. 1971 Jan;106(1):181-90.
8
Secretion of IgA in the sheep following local antigenic stimulation.绵羊局部抗原刺激后IgA的分泌。
Immunology. 1970 Oct;19(4):613-20.
9
Serological properties of gamma-A antibodies to Escherichia coli present in human colostrum.人初乳中存在的抗大肠杆菌γ-A抗体的血清学特性。
Immunology. 1966 Jun;10(6):517-26.
10
The antigens of Vibrio cholerae involved in the vibriocidal action of antibody and complement.霍乱弧菌的抗原参与抗体和补体的杀弧菌作用。
J Infect Dis. 1970 May;121(5):505-13. doi: 10.1093/infdis/121.5.505.