• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

系统性红斑狼疮中的抗淋巴细胞抗体。对淋巴细胞表面特征的影响。

Antilymphocyte antibodies in systemic lupus erythematosus. Effect on lymphocyte surface characteristics.

作者信息

Messner R P, Kennedy M S, Jelinek J G

出版信息

Arthritis Rheum. 1975 May-Jun;18(3):201-6. doi: 10.1002/art.1780180302.

DOI:10.1002/art.1780180302
PMID:1095019
Abstract

Antilymphocyte antibodies in SLE bind to normal lymphocytes and are not always associated with lymphocytotoxic activity. Detection of these antibodies on the surface of normal lymphocytes by immunofluorescent techniques is enhanced by short incubation periods, reduced temperature, and metabolic inhibition. The same effects occur in SLE blood and may influence the enumeration of B lymphocytes as determined by surface immunoglobulin. The percent of T lymphocytes forming sheep erythrocyte rosettes is not affected by these antibodies.

摘要

系统性红斑狼疮(SLE)中的抗淋巴细胞抗体可与正常淋巴细胞结合,且并不总是与淋巴细胞毒性活性相关。通过免疫荧光技术在正常淋巴细胞表面检测这些抗体时,短孵育期、降低温度和代谢抑制可增强检测效果。SLE血液中也会出现同样的效应,且可能影响通过表面免疫球蛋白测定的B淋巴细胞计数。形成绵羊红细胞玫瑰花结的T淋巴细胞百分比不受这些抗体影响。

相似文献

1
Antilymphocyte antibodies in systemic lupus erythematosus. Effect on lymphocyte surface characteristics.系统性红斑狼疮中的抗淋巴细胞抗体。对淋巴细胞表面特征的影响。
Arthritis Rheum. 1975 May-Jun;18(3):201-6. doi: 10.1002/art.1780180302.
2
Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus.系统性红斑狼疮中针对淋巴细胞表面决定簇的冷反应性抗体的性质。
Arthritis Rheum. 1975 Jan-Feb;18(1):1-8. doi: 10.1002/art.1780180101.
3
Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies.类风湿性关节炎和系统性红斑狼疮患者淋巴细胞分析。干扰性冷反应性抗淋巴细胞抗体的出现。
J Clin Invest. 1974 Nov;54(5):1082-92. doi: 10.1172/JCI107852.
4
Erythrocyte rosette inhibition as an assay for naturally occurring T lymphocytotoxic antibody in systemic lupus erythematosus.红细胞玫瑰花结抑制试验作为系统性红斑狼疮中自然存在的T淋巴细胞毒性抗体的一种检测方法。
Arthritis Rheum. 1979 Oct;22(10):1064-73. doi: 10.1002/art.1780221004.
5
Association of cold-reactive antilymphocyte antibodies with lymphopenia in systemic lupus erythematosus.系统性红斑狼疮中冷反应性抗淋巴细胞抗体与淋巴细胞减少的关联。
Arthritis Rheum. 1975 Nov-Dec;18(6):587-94. doi: 10.1002/art.1780180609.
6
Immunoglobulin class of antilymphocyte antibodies in systemic lupus erythematosus patients and their families.系统性红斑狼疮患者及其家族中抗淋巴细胞抗体的免疫球蛋白类别。
Acta Pathol Microbiol Scand C. 1977 Dec;85C(6):463-8. doi: 10.1111/j.1699-0463.1977.tb03669.x.
7
Monocyte-reactive antibodies in patients with systemic lupus erythematosus.系统性红斑狼疮患者体内的单核细胞反应性抗体。
Arthritis Rheum. 1977 Jun;20(5):1049-57. doi: 10.1002/art.1780200503.
8
Lymphocytotoxic antibodies in systemic lupus erythematosus patients and their relatives: reactivity with the HLA antigenic molecular complex.系统性红斑狼疮患者及其亲属体内的淋巴细胞毒性抗体:与HLA抗原分子复合物的反应性
Arthritis Rheum. 1980 Mar;23(3):265-72. doi: 10.1002/art.1780230301.
9
Anti-lymphocyte antibodies in systemic lupus erythematosus.系统性红斑狼疮中的抗淋巴细胞抗体。
Clin Rheum Dis. 1985 Dec;11(3):523-49.
10
Lymphocyte destruction by antibody-dependent cellular cytotoxicity mediated in vitro by antibodies in serum from patients with systemic lupus erythematosus.系统性红斑狼疮患者血清中的抗体在体外介导的抗体依赖性细胞毒性导致淋巴细胞破坏。
Ann Rheum Dis. 1982 Dec;41(6):593-8. doi: 10.1136/ard.41.6.593.

引用本文的文献

1
Antilymphocyte antibodies in systemic lupus erythematosus: association with disease activity and lymphopenia.系统性红斑狼疮中的抗淋巴细胞抗体:与疾病活动和淋巴细胞减少相关。
J Immunol Res. 2014;2014:672126. doi: 10.1155/2014/672126. Epub 2014 Apr 17.
2
Familial systemic lupus erythematosus: the role of genetic and environmental factors.家族性系统性红斑狼疮:遗传和环境因素的作用
Ann Rheum Dis. 2002 Jan;61(1):29-31. doi: 10.1136/ard.61.1.29.
3
Lymphocyte destruction by antibody-dependent cellular cytotoxicity mediated in vitro by antibodies in serum from patients with systemic lupus erythematosus.
系统性红斑狼疮患者血清中的抗体在体外介导的抗体依赖性细胞毒性导致淋巴细胞破坏。
Ann Rheum Dis. 1982 Dec;41(6):593-8. doi: 10.1136/ard.41.6.593.
4
Lymphocyte subpopulations and surface membrane immunoglobulins in myasthenia gravis.重症肌无力中的淋巴细胞亚群和表面膜免疫球蛋白
J Neurol Neurosurg Psychiatry. 1982 Feb;45(2):158-61. doi: 10.1136/jnnp.45.2.158.
5
Antibodies to T cells in patients with systemic lupus erythematosus can induce antibody-dependent cell-mediated cytotoxicity against human T cells.系统性红斑狼疮患者体内针对T细胞的抗体可诱导对人T细胞的抗体依赖性细胞介导的细胞毒性。
J Clin Invest. 1981 Mar;67(3):605-14. doi: 10.1172/JCI110074.
6
Use of the ELISA to screen for anti-thymocyte and anti-beta 2-microglobulin antibodies in leprosy and SLE.酶联免疫吸附测定法用于筛查麻风病和系统性红斑狼疮患者体内的抗胸腺细胞抗体及抗β2微球蛋白抗体。
Immunology. 1980 Dec;41(4):865-73.
7
The significance of antilymphocyte antibodies in patients with acquired immune deficiency syndrome (AIDS) and their sexual partners.抗淋巴细胞抗体在获得性免疫缺陷综合征(艾滋病)患者及其性伴侣中的意义。
J Clin Immunol. 1987 Mar;7(2):130-9. doi: 10.1007/BF00916007.
8
Study of lymphocyte subpopulations in normal humans and patients with systemic lupus erythematosus by fractionation of peripheral blood lymphocytes on a discontinuous Ficoll gradient.通过在不连续的Ficoll梯度上对外周血淋巴细胞进行分级分离,研究正常人和系统性红斑狼疮患者的淋巴细胞亚群。
Clin Exp Immunol. 1976 Nov;26(2):228-38.
9
Lymphocytes in rheumatoid and nonrheumatoid synovial fluids. Nonspecificity of high T-cell and low B-cell percentages.类风湿性和非类风湿性滑液中的淋巴细胞。高T细胞百分比和低B细胞百分比的非特异性。
Ann Rheum Dis. 1975 Oct;35(5):451-5. doi: 10.1136/ard.35.5.451.
10
Fc-rosette inhibition by hypocomplementaemic systemic lupus erythematosus sera.低补体血症系统性红斑狼疮血清对Fc玫瑰花结的抑制作用。
Ann Rheum Dis. 1975 Oct;35(5):415-21. doi: 10.1136/ard.35.5.415.