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1
Use of the ELISA to screen for anti-thymocyte and anti-beta 2-microglobulin antibodies in leprosy and SLE.酶联免疫吸附测定法用于筛查麻风病和系统性红斑狼疮患者体内的抗胸腺细胞抗体及抗β2微球蛋白抗体。
Immunology. 1980 Dec;41(4):865-73.
2
Modulation of IgM anti-lymphocyte antibody-reactive T cell surface antigens in systemic lupus erythematosus.系统性红斑狼疮中IgM抗淋巴细胞抗体反应性T细胞表面抗原的调节
J Immunol. 1986 May 1;136(9):3246-53.
3
Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results.通过酶联免疫吸附测定（ELISA）检测抗心磷脂抗体：结果的标准化与定量分析
Clin Exp Immunol. 1985 Dec;62(3):738-45.
4
IgG anti-lymphocyte antibodies in systemic lupus erythematosus react with surface molecules shared by peripheral T cells and a primitive T cell line.系统性红斑狼疮中的IgG抗淋巴细胞抗体与外周T细胞和原始T细胞系共有的表面分子发生反应。
J Immunol. 1987 Mar 15;138(6):1750-6.
5
Anti-beta2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome.在系统性红斑狼疮和抗磷脂综合征患者的纵向研究中检测抗β2糖蛋白I、抗凝血酶原和抗心磷脂抗体
Br J Rheumatol. 1998 Oct;37(10):1089-94.
6
IgG subclass distribution of anticardiolipin antibody in patients with systemic lupus erythematosus.系统性红斑狼疮患者抗心磷脂抗体的IgG亚类分布
J Rheumatol. 1988 Dec;15(12):1764-7.
7
The association of antibodies to cardiolipin, beta 2-glycoprotein I, prothrombin, and oxidized low-density lipoprotein with thrombosis in 292 patients with familial and sporadic systemic lupus erythematosus.292例家族性和散发性系统性红斑狼疮患者中抗心磷脂、β2-糖蛋白I、凝血酶原和氧化型低密度脂蛋白抗体与血栓形成的关联
Scand J Rheumatol. 2004;33(4):246-52. doi: 10.1080/03009740410005386.
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VH4-34 encoded antibody in systemic lupus erythematosus: effect of isotype.系统性红斑狼疮中VH4-34编码抗体：同种型的影响
J Rheumatol. 2002 Oct;29(10):2114-21.
9
Antigranulocyte antibodies in patients with systemic lupus erythematosus (SLE).
Acta Med Hung. 1987;44(4):299-310.
10
Distinguishing features of anti-beta2 glycoprotein I antibodies between patients with leprosy and the antiphospholipid syndrome.麻风病患者与抗磷脂综合征患者抗β2糖蛋白I抗体的鉴别特征。
Thromb Haemost. 2002 Apr;87(4):599-605.

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1
Antibodies to Mycobacterium paratuberculosis and nine species of environmental mycobacteria in Crohn's disease and control subjects.克罗恩病患者及对照人群中抗副结核分枝杆菌和九种环境分枝杆菌的抗体
Gut. 1993 Mar;34(3):371-4. doi: 10.1136/gut.34.3.371.
2
Absence of antibodies to muramyl dipeptide in patients with tuberculosis or leprosy.结核病或麻风病患者中缺乏针对胞壁酰二肽的抗体。
Clin Exp Immunol. 1982 Jan;47(1):53-8.
3
Biological and antigenic similarities of murine interferon-gamma and macrophage-activating factor.小鼠干扰素-γ与巨噬细胞激活因子的生物学及抗原相似性
J Exp Med. 1984 Mar 1;159(3):812-27. doi: 10.1084/jem.159.3.812.
4
Characterization of polyclonal autoantibodies specific for beta 2-microglobulin in multiple myeloma sera.多发性骨髓瘤血清中针对β2微球蛋白的多克隆自身抗体的特性分析。
Clin Exp Immunol. 1983 Dec;54(3):689-96.
5
Marked enhancement in vivo of adjuvant activity of muramyl dipeptide to protein antigens and to synthetic weak immunogens with monoclonal anti-muramyl dipeptide antibodies.用单克隆抗胞壁酰二肽抗体在体内显著增强胞壁酰二肽对蛋白质抗原和合成弱免疫原的佐剂活性。
Infect Immun. 1985 Aug;49(2):312-9. doi: 10.1128/iai.49.2.312-319.1985.
6
Enzyme immunoassay of serum beta-2-microglobulin levels in various histological forms of leprosy with special reference to its elevation in type I and type II lepra reactions.不同组织学类型麻风血清β2-微球蛋白水平的酶免疫测定，特别提及Ⅰ型和Ⅱ型麻风反应中其水平的升高
J Clin Microbiol. 1985 Apr;21(4):658-61. doi: 10.1128/jcm.21.4.658-661.1985.
7
Characterization of a factor in leprosy serum that inhibits the growth of mitogen-stimulated normal human lymphocytes.麻风血清中一种抑制丝裂原刺激的正常人淋巴细胞生长的因子的特性分析。
Immunology. 1987 Jun;61(2):117-23.
8
Comparison between autoantibodies in malaria and leprosy with lupus.疟疾和麻风病中的自身抗体与狼疮的比较。
Clin Exp Immunol. 1987 Dec;70(3):529-37.
9
HLA-DR-associated isotype-specific regulation of antibody levels to mycobacteria in rheumatoid arthritis.类风湿关节炎中HLA - DR相关的针对分枝杆菌抗体水平的同种型特异性调节
Clin Exp Immunol. 1988 Apr;72(1):26-31.
10
Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis.与HLA类型相关的抗分枝杆菌抗体水平：类风湿关节炎中存在与HLA无关的针对牛分枝杆菌65kD热休克蛋白的高水平抗体的证据。
Clin Exp Immunol. 1988 Nov;74(2):211-5.

本文引用的文献

1
CYTOTOXIC ISO-ANTIBODIES AGAINST LEUCOCYTES.
Vox Sang. 1965 Mar-Apr;10:228-33. doi: 10.1111/j.1423-0410.1965.tb04345.x.
2
Fetomaternal leukocyte incompatibility.母胎白细胞不相容性。
J Clin Invest. 1958 Dec;37(12):1756-63. doi: 10.1172/JCI103768.
3
Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test.同种移植的血清分型。18. 微滴淋巴细胞细胞毒性试验的改进。
Transplantation. 1968 Nov;6(8):913-27. doi: 10.1097/00007890-196811000-00006.
4
Immunological aspects of leprosy with special reference to autoimmune diseases.麻风病的免疫学方面，特别提及自身免疫性疾病
Bull World Health Organ. 1969;41(6):793-804.
5
Antibodies against cell membrane constituents in systemic lupus erythematosus and related diseases. I. Cytotoxic effect of serum from patients with systemic lupus erythematosus (SLE) for allogeneic and for autologous lymphocytes.系统性红斑狼疮及相关疾病中针对细胞膜成分的抗体。I. 系统性红斑狼疮（SLE）患者血清对同种异体和自体淋巴细胞的细胞毒性作用。
Clin Exp Immunol. 1971 Apr;8(4):543-50.
6
Cytotoxins in disease. V. Various diseases.疾病中的细胞毒素。五、各种疾病。
Transplant Proc. 1971 Mar;3(1):112-4.
7
Preparation and properties of lymphocyte plasma membrane.淋巴细胞质膜的制备与特性
Contemp Top Mol Immunol. 1974;3:27-56. doi: 10.1007/978-1-4684-2838-4_2.
8
Subpopulations of human lymphocytes defined by 2 -microglobulin.由β2-微球蛋白定义的人类淋巴细胞亚群。
J Immunol. 1973 Aug;111(2):609-17.
9
Antibodies to a specific surface antigen of T cells in human sera inhibiting mixed leukocyte culture reactions.人血清中针对T细胞特定表面抗原的抗体可抑制混合淋巴细胞培养反应。
J Exp Med. 1973 Oct 1;138(4):1021-6. doi: 10.1084/jem.138.4.1021.
10
Evaluation of the RAHA test for rheumatoid factor.类风湿因子的RAHA试验评估。
Med Lab Technol. 1974 Oct;31(4):323-6.

酶联免疫吸附测定法用于筛查麻风病和系统性红斑狼疮患者体内的抗胸腺细胞抗体及抗β2微球蛋白抗体。

Use of the ELISA to screen for anti-thymocyte and anti-beta 2-microglobulin antibodies in leprosy and SLE.

作者信息

Bahr G M, Rook G A, Moreno E, Lydyard P M, Modabber F Z, Stanford J L

出版信息

Immunology. 1980 Dec;41(4):865-73.

PMID:6161879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1458311/
Abstract

A report is given of the use of the enzyme-linked immunosorbent assay to measure antibody to preparations of human thymocyte membranes (HTMA) and to beta 2-microglobulin. The assay described is simple and rapid, and requires only small quantities of an easily stored membrane preparation. The advantages of this technique over conventional methods involving cytotoxicity are discussed. Raised levels of IgM antibody to beta 2-microglobulin were detected in sera from SLE patients. Raised levels of IgG and IgM antibody to HTMA were found in sera from most active lepromatous cases. Two of eight sera from SLE patients showed raised IgG anti-HMTA, but not raised IgM. An attempt was made to study the subclass of the IgG antibodies found, but when checked against purified human IgG myeloma proteins, the available anti-subclass sera were found to lack the necessary degree of specificity in this assay.

摘要

本文报道了用酶联免疫吸附测定法检测人胸腺细胞膜（HTMA）制剂抗体和β2微球蛋白抗体。所述测定法简单快速，仅需少量易于保存的膜制剂。讨论了该技术相对于涉及细胞毒性的传统方法的优势。在系统性红斑狼疮（SLE）患者血清中检测到抗β2微球蛋白IgM抗体水平升高。在大多数活动性瘤型麻风病例的血清中发现抗HTMA的IgG和IgM抗体水平升高。8例SLE患者血清中有2例显示抗HMTA IgG升高，但IgM未升高。尝试研究所发现的IgG抗体的亚类，但在与纯化的人IgG骨髓瘤蛋白对照检查时，发现可用的抗亚类血清在此测定法中缺乏必要的特异性程度。