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男性生殖介导的风险:农药施用者妻子中的自然流产情况。

Reproductive male-mediated risk: spontaneous abortion among wives of pesticide applicators.

作者信息

Petrelli G, Figà-Talamanca I, Tropeano R, Tangucci M, Cini C, Aquilani S, Gasperini L, Meli P

机构信息

Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità, Roma, Italia.

出版信息

Eur J Epidemiol. 2000 Apr;16(4):391-3. doi: 10.1023/a:1007630610911.

Abstract

This study was conducted among 32 pesticide applicators occupationally exposed to pesticides to determine whether paternal exposure is associated with an increased risk of spontaneous abortion. The ratio of abortion was compared between applicators and a group of 51 food retailers (control population). The ratio of abortions/pregnancies for applicators was 0.27 and for retailers 0.07. OR for spontaneous abortion adjusted for age of wife and smoking of parents is 3.8 times greater than for the control population in the multiple logistic regression model and 7.6 times with interaction effects model.

摘要

本研究针对32名职业性接触农药的施药人员开展,以确定父亲接触农药是否会增加自然流产风险。将施药人员与51名食品零售商(对照人群)的流产率进行比较。施药人员的流产/妊娠比为0.27,零售商为0.07。在多元逻辑回归模型中,经妻子年龄和父母吸烟情况调整后的自然流产优势比是对照人群的3.8倍,在交互效应模型中为7.6倍。

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