减数分裂过程中重组起始时染色体DNA的单链断裂。
Single-strand scissions of chromosomal DNA during commitment to recombination at meiosis.
作者信息
Jacobson G K, Pinon R, Esposito R E, Esposito M S
出版信息
Proc Natl Acad Sci U S A. 1975 May;72(5):1887-91. doi: 10.1073/pnas.72.5.1887.
Abstract
Diploid cells of the yeast Saccharomyces cerevisiae induced to undergo meiosis accumulate single-strand scissions in both template and newly synthesized DNA during commitment to genetic recombination. No evidence for accumulation of double-strand breaks during meiosis was obtained. When commitment to recombination is at the full meiotic level there are approximately 70 to 200 single-strand scissions per meiotic cell in which approximately 150 recombination events have been reported to occur.
摘要
经诱导进行减数分裂的酿酒酵母二倍体细胞在进行遗传重组过程中，模板DNA和新合成的DNA都会积累单链断裂。未获得减数分裂过程中双链断裂积累的证据。当重组达到完全减数分裂水平时，每个减数分裂细胞中大约有70至200个单链断裂，据报道其中大约发生了150次重组事件。
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