酶联免疫吸附测定（ELISA）在梅毒血清学诊断中的应用。
Application of the enzyme-linked immunosorbent assay (ELISA) in the serodiagnosis of syphilis.
作者信息
Veldkamp J, Visser A M
出版信息
Br J Vener Dis. 1975 Aug;51(4):227-31. doi: 10.1136/sti.51.4.227.
Abstract
The enzyme-linked immunosorbent assay (ELISA) technique, using an ultrasonicate of Treponema pallidum as antigen, has been evaluated as a serological test for syphilis. It is concluded that the test is simple, reliable, and relatively quick and that its sensitivity in all stages of syphilis is equal to the FTAABS test. Because its specificity is probably also high, ELISA might be used in future as a first-line screening test for the serodiagnosis of syphilis.
摘要
以梅毒螺旋体超声提取物为抗原的酶联免疫吸附测定（ELISA）技术已被评估为梅毒的血清学检测方法。得出的结论是，该检测方法简单、可靠且相对快速，并且其在梅毒各阶段的敏感性与荧光密螺旋体抗体吸收试验（FTA-ABS试验）相当。由于其特异性可能也很高，ELISA未来可能用作梅毒血清学诊断的一线筛查试验。
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