利福平对大肠杆菌dnaC突变体中噬菌体phiX174亲本复制型DNA合成的抑制作用。
Rifampin inhibition of bacteriophage phiX174 parental replicative-form DNA synthesis in an Escherichia coli dnaC mutant.
作者信息
Dumas L B, Miller C A, Bayne M L
出版信息
J Virol. 1975 Sep;16(3):575-80. doi: 10.1128/JVI.16.3.575-580.1975.
Abstract
The Escherichia coli dnaC protein is not absolutely required in vivo for bacteriophage phiX174 parental replicative-form synthesis (Kranias and Dumas, 1974). However, when rifampin is present at a concentration that inhibits DNA-dependent RNA polymerase, phiX174 parental replicative-form synthesis is dependent on the dnaC protein activity. We conclude that E. coli DNA-dependent RNA polymerase can substitute for the dnaC protein in phiX174 parental replicative-form DNA synthesis, presumably in its initiation. The implications of this result with respect to the in vitro synthesis of the complementary strand of phiX174 DNA are discussed.
摘要
噬菌体φX174亲本复制型的合成在体内并非绝对需要大肠杆菌的dnaC蛋白（克拉尼亚斯和杜马斯，1974年）。然而，当利福平以抑制依赖DNA的RNA聚合酶的浓度存在时，φX174亲本复制型的合成依赖于dnaC蛋白的活性。我们得出结论，大肠杆菌依赖DNA的RNA聚合酶可以在φX174亲本复制型DNA合成中替代dnaC蛋白，大概是在其起始过程中。讨论了这一结果对体外合成φX174 DNA互补链的意义。
相似文献
1
Rifampin inhibition of bacteriophage phiX174 parental replicative-form DNA synthesis in an Escherichia coli dnaC mutant.利福平对大肠杆菌dnaC突变体中噬菌体phiX174亲本复制型DNA合成的抑制作用。
J Virol. 1975 Sep;16(3):575-80. doi: 10.1128/JVI.16.3.575-580.1975.
2
Inhibition of bacteriophage M13 and phix174 duplex DNA replication and single-strand synthesis in temperature-sensitive dnaZ mutants of Escherichia coli.大肠杆菌温度敏感型dnaZ突变体中噬菌体M13和phix174双链DNA复制及单链合成的抑制作用
J Virol. 1977 Apr;22(1):23-30. doi: 10.1128/JVI.22.1.23-30.1977.
3
Bacteriophage phiX174 single-stranded viral DNA synthesis in temperature-sensitive dnaB and dna C mutants of Escherichia coli.噬菌体φX174单链病毒DNA在大肠杆菌温度敏感型dnaB和dnaC突变体中的合成
J Virol. 1976 May;18(2):426-35. doi: 10.1128/JVI.18.2.426-435.1976.
4
Synthesis of complex forms of bacteriophage phiX174 double-stranded DNA in a temperature-sensitive dnaC mutant of Escherichia coli C.在大肠杆菌C的温度敏感型dnaC突变体中噬菌体phiX174双链DNA复杂形式的合成。
J Virol. 1975 Aug;16(2):412-9. doi: 10.1128/JVI.16.2.412-419.1975.
5
Replication of bacteriophage phiX174 DNA in a temperature-sensitive dnaC mutant of escherichia coli C.噬菌体phiX174 DNA在大肠杆菌C的温度敏感型dnaC突变体中的复制
J Virol. 1974 Jan;13(1):146-54. doi: 10.1128/JVI.13.1.146-154.1974.
6
Replication of bacteriophage phiK duplex replicative-form DNA in dnaB and dnaC mutants of Escherichia coli.噬菌体phiK双链复制型DNA在大肠杆菌dnaB和dnaC突变体中的复制
J Virol. 1979 Mar;29(3):840-5. doi: 10.1128/JVI.29.3.840-845.1979.
7
DNA synthesis in vitro dependent upon phiX174 replicative form I DNA.体外DNA合成依赖于φX174复制型I DNA。
Proc Natl Acad Sci U S A. 1976 Jun;73(6):1887-91. doi: 10.1073/pnas.73.6.1887.
8
Bacteriophage G4 DNA synthesis in temperature-sensitive dna mutants of Escherichia coli.噬菌体G4在大肠杆菌温度敏感型dna突变体中的DNA合成
J Virol. 1976 Sep;19(3):915-24. doi: 10.1128/JVI.19.3.915-924.1976.
9
Initiation of DNA synthesis on the isolated strands of bacteriophage f1 replicative-form DNA.噬菌体f1复制型DNA单链上DNA合成的起始
J Virol. 1979 Mar;29(3):1014-22. doi: 10.1128/JVI.29.3.1014-1022.1979.
10
Bacteriophage phi X174 DNA synthesis in Escherichia coli HF4704S (dnaHts) cells.噬菌体φX174 DNA在大肠杆菌HF4704S（dnaHts）细胞中的合成。
Biochim Biophys Acta. 1975 Jul 23;395(4):433-45. doi: 10.1016/0005-2787(75)90067-2.
引用本文的文献
1
Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response.大肠杆菌priA DNA复制蛋白的失活会诱导SOS反应。
J Bacteriol. 1991 Nov;173(21):6686-93. doi: 10.1128/jb.173.21.6686-6693.1991.
2
Deoxyribonucleic acid synthesis in a temperature-sensitive Escherichia coli dnaH mutant, strain HF4704S.温度敏感型大肠杆菌dnaH突变体HF4704S中的脱氧核糖核酸合成
J Bacteriol. 1976 Dec;128(3):801-9. doi: 10.1128/jb.128.3.801-809.1976.
3
Bacteriophage G4 DNA synthesis in temperature-sensitive dna mutants of Escherichia coli.噬菌体G4在大肠杆菌温度敏感型dna突变体中的DNA合成
J Virol. 1976 Sep;19(3):915-24. doi: 10.1128/JVI.19.3.915-924.1976.
4
Novel replicative properties of a capsid mutant of bacteriophage phi chi 174.噬菌体φX174衣壳突变体的新型复制特性
J Virol. 1976 Jun;18(3):942-9. doi: 10.1128/JVI.18.3.942-949.1976.
5
Host cell DNA chain initiation protein requirements for replication of bacteriophage G4 replicative-form DNA.
J Virol. 1979 Aug;31(2):370-5. doi: 10.1128/JVI.31.2.370-375.1979.
6
Replication of bacteriophage phiK duplex replicative-form DNA in dnaB and dnaC mutants of Escherichia coli.噬菌体phiK双链复制型DNA在大肠杆菌dnaB和dnaC突变体中的复制
J Virol. 1979 Mar;29(3):840-5. doi: 10.1128/JVI.29.3.840-845.1979.
7
Inhibition of bacteriophage M13 and phix174 duplex DNA replication and single-strand synthesis in temperature-sensitive dnaZ mutants of Escherichia coli.大肠杆菌温度敏感型dnaZ突变体中噬菌体M13和phix174双链DNA复制及单链合成的抑制作用
J Virol. 1977 Apr;22(1):23-30. doi: 10.1128/JVI.22.1.23-30.1977.
本文引用的文献
1
The process of infection with bacteriophage phi-X174. 3. Phage maturation and lysis after synchronized infection.噬菌体φ-X174的感染过程。3. 同步感染后的噬菌体成熟与裂解。
J Mol Biol. 1965 Jul;12(3):641-6. doi: 10.1016/s0022-2836(65)80318-7.
2
Escherichia coli mutants temperature-sensitive for DNA synthesis.对DNA合成温度敏感的大肠杆菌突变体。
Mol Gen Genet. 1971;113(3):273-84. doi: 10.1007/BF00339547.
3
Transcription: role in the initiation and replication of DNA synthesis in Escherichia coli and phiX174.转录：在大肠杆菌和φX174中DNA合成起始和复制中的作用。
Biochim Biophys Acta. 1971 Oct;247(3):383-90. doi: 10.1016/0005-2787(71)90023-2.
4
Escherichia coli mutants with temperature-sensitive synthesis of DNA.具有温度敏感型DNA合成能力的大肠杆菌突变体。
Mol Gen Genet. 1970;109(2):107-22. doi: 10.1007/BF00269647.
5
Stages in the replication of bacteriophage phi X174 DNA in vivo.噬菌体φX174 DNA在体内的复制阶段。
Cold Spring Harb Symp Quant Biol. 1968;33:443-7. doi: 10.1101/sqb.1968.033.01.051.
6
Mode of action of rafamycin on the RNA polymerase reaction.雷法霉素对RNA聚合酶反应的作用模式。
Biochim Biophys Acta. 1968 Mar 18;157(1):218-9. doi: 10.1016/0005-2787(68)90286-4.
7
Multienzyme systems of DNA replication.DNA复制的多酶系统
Science. 1974 Dec 13;186(4168):987-93. doi: 10.1126/science.186.4168.987.
8
A novel form of RNA polymerase from Escherichia coli.来自大肠杆菌的一种新型RNA聚合酶。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4425-8. doi: 10.1073/pnas.71.11.4425.
9
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins.用纯化的大肠杆菌蛋白将φX174病毒DNA转化为双链形式。
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4120-4. doi: 10.1073/pnas.71.10.4120.
10
Inhibition of bacteriophage phi chi 174 DNA replication in dnaB mutants of Escherichia coli C.大肠杆菌C的dnaB突变体中噬菌体φX174 DNA复制的抑制作用。
J Virol. 1974 Dec;14(6):1369-79. doi: 10.1128/JVI.14.6.1369-1379.1974.
Zotero 插件