Suppr超能文献

噬菌体φX174衣壳突变体的新型复制特性

Novel replicative properties of a capsid mutant of bacteriophage phi chi 174.

作者信息

Vito C C, Dowell C E

出版信息

J Virol. 1976 Jun;18(3):942-9. doi: 10.1128/JVI.18.3.942-949.1976.

Abstract

A capsid mutant of bacteriophage phi chi 174 demonstrates altered requirements for the conversion of viral single-stranded DNA to double-stranded replicative form DNA. In the presence of puromycin at 42 C, wild-type phi chi 174 is unable to complete this replicative event, whereas phi chi ahb is able to do so. Furthermore, in contrast to wild-type phi chi 174, formation of phi chi ahb parental replicative form DNA is sensitive to rifampin under certain experimental conditions. These data suggest that the mutant capsid proteins of phi chi ahb influence the biosynthesis of phi chi ahb complementary strand DNA.

摘要

噬菌体φX174的一种衣壳突变体显示出对病毒单链DNA转化为双链复制型DNA的需求发生了改变。在42℃下存在嘌呤霉素时,野生型φX174无法完成这一复制过程,而φX ahb则能够完成。此外,与野生型φX174不同,在某些实验条件下,φX ahb亲本复制型DNA的形成对利福平敏感。这些数据表明,φX ahb的突变衣壳蛋白影响了φX ahb互补链DNA的生物合成。

相似文献

本文引用的文献

5
Stages in the replication of bacteriophage phi X174 DNA in vivo.噬菌体φX174 DNA在体内的复制阶段。
Cold Spring Harb Symp Quant Biol. 1968;33:443-7. doi: 10.1101/sqb.1968.033.01.051.
7
Multienzyme systems of DNA replication.DNA复制的多酶系统
Science. 1974 Dec 13;186(4168):987-93. doi: 10.1126/science.186.4168.987.
8
A novel form of RNA polymerase from Escherichia coli.来自大肠杆菌的一种新型RNA聚合酶。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4425-8. doi: 10.1073/pnas.71.11.4425.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验