纤维肌痛患者与慢性疲劳综合征患者的疼痛主诉
Pain complaints in patients with fibromyalgia versus chronic fatigue syndrome.
作者信息
Bradley L A, McKendree-Smith N L, Alarcón G S
机构信息
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, School of Medicine, 475 Boshell Diabetes Building, 1808 7th Avenue South, Birmingham, AL 35294, USA.
出版信息
Curr Rev Pain. 2000;4(2):148-57. doi: 10.1007/s11916-000-0050-2.
Individuals with fibromyalgia (FM) and/or chronic fatigue syndrome (CFS) report arthralgias and myalgias. However, only persons with FM alone exhibit abnormal pain responses to mild levels of stimulation, or allodynia. We identify the abnormalities in the neuroendocrine axes that are common to FM and CFS as well as the abnormalities in central neuropeptide levels and functional brain activity that differentiate these disorders. These two sets of factors, respectively, may account for the similarities and differences in the pain experiences of persons with FM and CFS.
患有纤维肌痛（FM）和/或慢性疲劳综合征（CFS）的个体报告有关节痛和肌痛。然而，只有单纯患有FM的个体对轻度刺激表现出异常的疼痛反应，即痛觉过敏。我们确定了FM和CFS共有的神经内分泌轴异常，以及区分这些疾病的中枢神经肽水平和大脑功能活动异常。这两组因素可能分别解释了FM和CFS患者疼痛体验的异同。
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