Buchwald D
Department of Medicine, University of Washington, Seattle, USA.
Rheum Dis Clin North Am. 1996 May;22(2):219-43. doi: 10.1016/s0889-857x(05)70270-2.
CFS and FM are clinical conditions characterized by a variety of nonspecific symptoms including prominent fatigue, myalgia, and sleep disturbances. There are no diagnostic studies or widely accepted, pathogenic, explanatory models for either illness. Despite remarkably different diagnostic criteria, CFS and FM have many demographic and clinical similarities. More specifically, few differences exist in the domains of symptoms, examination findings, laboratory tests, functional status, psychosocial features, and psychiatric disorders. FM appears to represent an additional burden of suffering among those with CFS, however, underscoring the importance of recognizing concurrent CFS and FM. Further clarification of the similarities (and differences) between CFS and FM may be useful in studies of prognosis and help define subsets of patients who may benefit from specific therapeutic interventions.
慢性疲劳综合征（CFS）和纤维肌痛（FM）是临床病症，其特征为多种非特异性症状，包括显著疲劳、肌痛和睡眠障碍。这两种病症均没有诊断性研究或被广泛接受的、致病的、解释性模型。尽管诊断标准差异显著，但CFS和FM在人口统计学和临床方面有许多相似之处。更具体地说，在症状、检查结果、实验室检查、功能状态、心理社会特征和精神障碍等领域几乎没有差异。然而，FM似乎给CFS患者带来了额外的痛苦负担，这凸显了识别CFS和FM共病的重要性。进一步阐明CFS和FM之间的异同可能有助于预后研究，并有助于确定可能从特定治疗干预中获益的患者亚组。
