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噬菌体φA和噬菌体φX174在DNA合成中对温度敏感的大肠杆菌突变体中的复制。

Replication of phiA and phiX174 in Escherichia coli mutants thermosensitive in DNA synthesis.

作者信息

Taketo A

出版信息

Mol Gen Genet. 1975 Sep 8;139(4):285-91. doi: 10.1007/BF00267968.

DOI:10.1007/BF00267968
PMID:1102942
Abstract

Thermosensitive mutants of E. coli defective in DNA replication were tested for their capacity to support multiplication of phiA and phiX174. At the restrictive temperature, the viral growth was markedly affected in dnaH, dnaZ, or ligts7 mutants. Even when these strains were transfected with RF1 molecules, the virus yield was still very low. The dnaI function was, however, dispensable for replication of phiA and phiX174. In addition, these viruses could multiply in dnaP or polAts mutants at the high temperature.

摘要

对在DNA复制方面存在缺陷的大肠杆菌温度敏感突变体进行了测试，以检测它们支持噬菌体φA和噬菌体φX174增殖的能力。在限制温度下，dnaH、dnaZ或ligts7突变体中的病毒生长受到显著影响。即使这些菌株用RF1分子进行转染，病毒产量仍然非常低。然而，dnaI功能对于噬菌体φA和噬菌体φX174的复制是可有可无的。此外，这些病毒能够在高温下在dnaP或polAts突变体中增殖。

相似文献

1
Replication of phiA and phiX174 in Escherichia coli mutants thermosensitive in DNA synthesis.噬菌体φA和噬菌体φX174在DNA合成中对温度敏感的大肠杆菌突变体中的复制。
Mol Gen Genet. 1975 Sep 8;139(4):285-91. doi: 10.1007/BF00267968.
2
Inducibility of lambda phage development in Escherichia coli mutants thermosensitive for DNA replication.
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Host genes involved in the replication of single-stranded DNA phage phiK.
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Growth of single-stranded DNA phages in replication mutants of Escherichia coli.单链DNA噬菌体在大肠杆菌复制突变体中的生长情况。
Mol Gen Genet. 1978 Jun 14;162(2):151-5. doi: 10.1007/BF00267871.
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Sensitivity of Escherichia coli to viral nucleic acid. VI. Capacity of dna mutants and DNA polymerase-less mutants for multiplication of phiA and phiX 174.大肠杆菌对病毒核酸的敏感性。VI. dna突变体和无DNA聚合酶突变体对噬菌体A和噬菌体X 174增殖的能力。
Mol Gen Genet. 1973 Mar 27;122(1):15-22. doi: 10.1007/BF00337970.
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The mechanism of replication of phiX174 DNA. XIII. Discontinuous synthesis of the complementary strand in an Escherichia coli host with a temperature-sensitive polynucleotide ligase.φX174 DNA的复制机制。 XIII. 在具有温度敏感型多核苷酸连接酶的大肠杆菌宿主中互补链的不连续合成。
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Lysogenization of Escherichia coli by bacteriophage Lambda: complementary activity of the host's DNA polymerase I and ligase and bacteriophage replication proteins Q and P.噬菌体λ对大肠杆菌的溶原化作用：宿主DNA聚合酶I和连接酶以及噬菌体复制蛋白Q和P的互补活性
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Conversion of bacteriophage G4 single-stranded viral DNA to double-stranded replicative form in dna mutants of Escherichia coli.噬菌体G4单链病毒DNA在大肠杆菌的dna突变体中转化为双链复制形式。
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Host factors involved in the growth of microvirid phage alpha 3.
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引用本文的文献

1
Host genes involved in the replication of single-stranded DNA phage phiK.
Mol Gen Genet. 1976 Oct 18;148(1):25-9. doi: 10.1007/BF00268542.
2
Deoxyribonucleic acid synthesis in a temperature-sensitive Escherichia coli dnaH mutant, strain HF4704S.温度敏感型大肠杆菌dnaH突变体HF4704S中的脱氧核糖核酸合成
J Bacteriol. 1976 Dec;128(3):801-9. doi: 10.1128/jb.128.3.801-809.1976.
3
Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III.大肠杆菌DNA聚合酶III、dnaZ蛋白以及DNA延伸因子I和III催化的DNA延伸机制。

本文引用的文献

1
Escherichia coli mutants temperature-sensitive for DNA synthesis.对DNA合成温度敏感的大肠杆菌突变体。
Mol Gen Genet. 1971;113(3):273-84. doi: 10.1007/BF00339547.
2
Polynucleotide ligase and phiX174 single strand synthesis.多核苷酸连接酶与φX174单链合成
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Bacteriophage phi-X174 and related viruses.噬菌体φ-X174及相关病毒。
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Mol Gen Genet. 1976 Oct 18;148(2):139-42. doi: 10.1007/BF00268377.
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DNA synthesis in vitro dependent upon phiX174 replicative form I DNA.体外DNA合成依赖于φX174复制型I DNA。
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Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro.大肠杆菌dnaZ基因产物参与体外DNA延伸过程。
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Functional relationship between bacteriophages G4 and phi X174.噬菌体G4与噬菌体φX174之间的功能关系。
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Growth and DNA synthesis of bacteriophage phi x174 in a dnaP mutant of Escherichia coli.噬菌体φX174在大肠杆菌dnaP突变体中的生长及DNA合成
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Growth of single-stranded DNA phages in replication mutants of Escherichia coli.单链DNA噬菌体在大肠杆菌复制突变体中的生长情况。
Mol Gen Genet. 1978 Jun 14;162(2):151-5. doi: 10.1007/BF00267871.
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Isolation and characterization of plaque-forming lambdadnaZ+ transducing bacteriophages.噬菌斑形成的λdnaZ⁺转导噬菌体的分离与鉴定
J Bacteriol. 1977 Apr;130(1):354-65. doi: 10.1128/jb.130.1.354-365.1977.
Prog Nucleic Acid Res Mol Biol. 1968;8:115-69.
4
Sensitivity of Escherichia coli to viral nucleic acid. 3. Competence of glycine-spheroplasts.大肠杆菌对病毒核酸的敏感性。3. 甘氨酸原生质球的感受态。
J Biochem. 1972 Mar;71(3):507-12.
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Multienzyme systems of DNA replication.DNA复制的多酶系统
Science. 1974 Dec 13;186(4168):987-93. doi: 10.1126/science.186.4168.987.
6
Replication of Escherichia coli requires DNA polymerase I.大肠杆菌的复制需要DNA聚合酶I。
Nature. 1974 Aug 9;250(5466):513-4. doi: 10.1038/250513a0.
7
Growth of phages lambda, phiX174, and Ml3 requires the dnaZ (previously dnaH) gene product of Escherichia coli.噬菌体λ、φX174和M13的生长需要大肠杆菌的dnaZ（以前称为dnaH）基因产物。
Biochem Biophys Res Commun. 1974 Dec 11;61(3):1036-42. doi: 10.1016/0006-291x(74)90259-9.
8
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins.用纯化的大肠杆菌蛋白将φX174病毒DNA转化为双链形式。
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4120-4. doi: 10.1073/pnas.71.10.4120.
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Properties of bacterial virus phi A and its DNA.细菌病毒φA及其DNA的特性。
J Biochem. 1974 May;75(5):951-60. doi: 10.1093/oxfordjournals.jbchem.a130497.
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Replication of deoxyribonucleic acid in Escherichia coli C mutants temperature sensitive in the initiation of chromosome replication.大肠杆菌C突变体中染色体复制起始温度敏感型的脱氧核糖核酸复制
J Bacteriol. 1974 Sep;119(3):811-20. doi: 10.1128/jb.119.3.811-820.1974.