Why Sackett's analysis of randomized controlled trials fails, but needn't.

作者信息

Shapiro S H, Glass K C

机构信息

Department of Epidemiology & Biostatistics, McGill University, Montreal, Que.

出版信息

CMAJ. 2000 Oct 3;163(7):834-5.

PMID:11033712

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC80507/

Abstract

摘要

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本文引用的文献

For and against: clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial.

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CMAJ. 2000 May 2;162(9):1311-4.

Trials: the next 50 years. Large scale randomised evidence of moderate benefits.

BMJ. 1998 Oct 31;317(7167):1170-1. doi: 10.1136/bmj.317.7167.1170.

Equipoise and the ethics of clinical research.

N Engl J Med. 1987 Jul 16;317(3):141-5. doi: 10.1056/NEJM198707163170304.

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