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本文引用的文献

1
Molecular epidemiology of plasmid spread among extended broad-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates in a pediatric hospital.一家儿童医院中产超广谱β-内酰胺酶肺炎克雷伯菌分离株间质粒传播的分子流行病学研究
J Clin Microbiol. 1993 Feb;31(2):179-84. doi: 10.1128/jcm.31.2.179-184.1993.
2
Epidemiological study by pulsed-field gel electrophoresis of an outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a geriatric hospital.一家老年医院中产超广谱β-内酰胺酶肺炎克雷伯菌暴发的脉冲场凝胶电泳流行病学研究。
J Clin Microbiol. 1994 Feb;32(2):301-5. doi: 10.1128/jcm.32.2.301-305.1994.
3
Epidemiological fingerprinting of Enterobacter cloacae by small-fragment restriction endonuclease analysis and pulsed-field gel electrophoresis of genomic restriction fragments.通过小片段限制性内切酶分析和基因组限制性片段的脉冲场凝胶电泳对阴沟肠杆菌进行流行病学指纹图谱分析。
J Clin Microbiol. 1993 Jan;31(1):128-33. doi: 10.1128/jcm.31.1.128-133.1993.
4
Clonal outbreaks of extended-spectrum beta-lactamase-producing strains of Klebsiella pneumoniae demonstrated by antibiotic susceptibility testing, beta-lactamase typing, and multilocus enzyme electrophoresis.通过抗生素敏感性试验、β-内酰胺酶分型和多位点酶电泳证实的产超广谱β-内酰胺酶肺炎克雷伯菌菌株的克隆暴发。
J Clin Microbiol. 1994 Oct;32(10):2625-7. doi: 10.1128/jcm.32.10.2625-2627.1994.
5
Molecular epidemiology of Klebsiella pneumoniae strains that produce SHV-4 beta-lactamase and which were isolated in 14 French hospitals.在14家法国医院分离出的产SHV-4β-内酰胺酶的肺炎克雷伯菌菌株的分子流行病学。
J Clin Microbiol. 1994 Oct;32(10):2553-8. doi: 10.1128/jcm.32.10.2553-2558.1994.
6
Detection of resistance due to inducible beta-lactamase in Enterobacter aerogenes and Enterobacter cloacae.产气肠杆菌和阴沟肠杆菌中诱导型β-内酰胺酶所致耐药性的检测
J Clin Microbiol. 1994 Oct;32(10):2481-6. doi: 10.1128/jcm.32.10.2481-2486.1994.
7
Contribution of chromosomal beta-lactamases to beta-lactam resistance in enterobacteria.染色体β-内酰胺酶在肠杆菌科细菌对β-内酰胺类抗生素耐药性中的作用。
Rev Infect Dis. 1986 Jul-Aug;8 Suppl 3:S292-304. doi: 10.1093/clinids/8.supplement_3.s292.
8
Novel plasmid-mediated beta-lactamase in members of the family Enterobacteriaceae from Ohio.来自俄亥俄州的肠杆菌科成员中新型质粒介导的β-内酰胺酶
Antimicrob Agents Chemother. 1986 Aug;30(2):220-4. doi: 10.1128/AAC.30.2.220.
9
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.产超广谱β-内酰胺酶导致肠杆菌科细菌对新型β-内酰胺类药物产生可转移耐药性：医院流行情况及药敏模式
Rev Infect Dis. 1988 Jul-Aug;10(4):867-78. doi: 10.1093/clinids/10.4.867.
10
Klebsiella pneumoniae and other Enterobacteriaceae producing novel plasmid-mediated beta-lactamases markedly active against third-generation cephalosporins: epidemiologic studies.肺炎克雷伯菌及其他产新型质粒介导的对第三代头孢菌素具有显著活性的β-内酰胺酶的肠杆菌科细菌：流行病学研究
Rev Infect Dis. 1988 Jul-Aug;10(4):850-9. doi: 10.1093/clinids/10.4.850.

重症监护病房中产 TEM-24 型产气肠杆菌的暴发以及超广谱β-内酰胺酶在肠杆菌科其他菌属中的传播。

Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae.

作者信息

Neuwirth C, Siebor E, Lopez J, Pechinot A, Kazmierczak A

机构信息

Laboratoire de Bactériologie, Hôpital Universitaire du Bocage, Dijon, France.

出版信息

J Clin Microbiol. 1996 Jan;34(1):76-9. doi: 10.1128/jcm.34.1.76-79.1996.

DOI:10.1128/jcm.34.1.76-79.1996
PMID:8748277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC228734/
Abstract

We report an outbreak of Enterobacter aerogenes in an intensive care unit (ICU) and two medicine departments that produced the extended-spectrum beta-lactamase TEM-24, which was difficult to detect by disk agar diffusion. The strains were compared by DNA restriction fragment length polymorphism after pulsed-field gel electrophoresis following cleavage with XbaI. This typing method indicated that a single strain, first isolated in the ICU, spread throughout the other medical departments as a result of patient transfer. We also observed the transfer in vivo of the plasmid encoding TEM-24 from the strain of Enterobacter aerogenes to different strains of Escherichia coli and Citrobacter freundii in the ICU. It therefore appears that the epidemic involved results from two events: dissemination of one strain of Enterobacter aerogenes and dissemination of the plasmid encoding TEM-24 among various members of the family Enterobacteriaceae.

摘要

我们报告了在一个重症监护病房（ICU）和两个内科病房爆发的产气肠杆菌疫情，这些菌株产生了超广谱β-内酰胺酶TEM-24，通过纸片琼脂扩散法很难检测到。在用XbaI酶切后，通过脉冲场凝胶电泳对菌株进行DNA限制性片段长度多态性分析。这种分型方法表明，最初在ICU分离出的单一菌株，由于患者转移而传播到了其他内科病房。我们还观察到，在ICU中，编码TEM-24的质粒在产气肠杆菌菌株与不同的大肠杆菌和弗氏柠檬酸杆菌菌株之间发生了体内转移。因此，此次疫情似乎是由两个事件导致的：一株产气肠杆菌的传播以及编码TEM-24的质粒在肠杆菌科各成员之间的传播。