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扁平苔藓与大疱性类天疱疮的共存。一项免疫病理学研究。

Coexistence of lichen planus and bullous pemphigoid. A immunopathological study.

作者信息

Stingl G, Holubar K

出版信息

Br J Dermatol. 1975 Sep;93(3):313-20. doi: 10.1111/j.1365-2133.1975.tb06497.x.

DOI:10.1111/j.1365-2133.1975.tb06497.x
PMID:1103935
Abstract

A 43-year-old white man presented with a generalized eruption of lichen planus and tense blisters within the lichenoid lesions and also on clinically normal skin. Direct immunofluorescence (IF) studies revealed immunological and histopathological characteristics of lichen planus in the lichenoid lesions and of bullous pemphigoid in the bullous lesions, and indirect IF studies showed that the patient had circulating antibasement membrane antibodies. The coexistence of both disorders may indicate a possible link between the pathology in the junctional zone in lichen planus and the appearance of antibasement membrane zone antibodies and bullous lesions, respectively.

摘要

一名43岁的白人男性,全身出现扁平苔藓样皮疹,在苔藓样皮损内及临床正常皮肤上有紧张性水疱。直接免疫荧光(IF)研究显示,苔藓样皮损具有扁平苔藓的免疫和组织病理学特征,水疱性皮损具有大疱性类天疱疮的特征,间接免疫荧光研究表明该患者存在循环抗基底膜抗体。两种疾病并存可能分别提示扁平苔藓交界区病理与抗基底膜带抗体及水疱性皮损出现之间存在潜在联系。

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Coexistence of lichen planus and bullous pemphigoid. A immunopathological study.扁平苔藓与大疱性类天疱疮的共存。一项免疫病理学研究。
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