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酒精和大麻对静态视力的影响。

Alcohol and marijuana effects on static visual acuity.

作者信息

Adams A J, Brown B, Flom M C, Jones R T, Jampolsky A

出版信息

Am J Optom Physiol Opt. 1975 Nov;52(11):729-35. doi: 10.1097/00006324-197511000-00001.

Abstract

Static visual acuity was measured at two contrast levels (12 and 49%) in ten subjects in a double blind experiment involving five drug conditions of alcohol and marijuana (0.5 ml and 1.0 ml/kg body weight of 95% ethanol, 8 and 15 mg delta-9-tetrahydrocannabinol (THC), and a placebo). We found no statistically significant change in static visual acuity for any of the dose levels at any of the measurement time up to six hours following drug ingestion; this is sharply contrasted with the marked decrements in acuity which were found in the same subjects under the same drug conditions when the targets were in motion and required corrdinated eye movements for their resolution.

摘要

在一项双盲实验中,对10名受试者在两种对比度水平(12%和49%)下测量了静态视力,该实验涉及酒精和大麻的五种药物条件(95%乙醇0.5毫升和1.0毫升/千克体重、8毫克和15毫克δ-9-四氢大麻酚(THC)以及一种安慰剂)。我们发现在药物摄入后的长达6小时内,任何测量时间的任何剂量水平下,静态视力均无统计学上的显著变化;这与在相同药物条件下,当目标移动且需要协调眼球运动来分辨时,在相同受试者中发现的视力显著下降形成鲜明对比。

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