通过吸烟摄入9-四氢大麻酚对人体的影响。

Effects on humans of 9 -tetrahydrocannabinol administered by smoking.

作者信息

Galanter M, Wyatt R J, Lemberger L, Weingartner H, Vaughan T B, Roth W T

出版信息

Science. 1972 May 26;176(4037):934-6. doi: 10.1126/science.176.4037.934.

DOI:10.1126/science.176.4037.934

Abstract

Twelve chronic marijuana users received triangle up(9)-tetrahydrocannabinol by smoking. The magnitude of their pulse increment was highly correlated with their subjective experiences. Three of the 12 subjects subsequently received triangle up(9)-tetrahydrocannabinol labeled with carbon-14; the time course of its concentration in plasma was highly correlated with the pulse increment. Subjective symptoms, however, appeared later and dissipated more slowly.

摘要

12名长期吸食大麻者通过吸烟摄入△⁹-四氢大麻酚。他们脉搏增加的幅度与主观体验高度相关。12名受试者中有3人随后摄入了用碳-14标记的△⁹-四氢大麻酚；其在血浆中的浓度随时间变化的过程与脉搏增加高度相关。然而，主观症状出现较晚且消散较慢。