Drueschke E E, Zaneveld L J, Burns M, Rodzen R, Wingfield J R, Maness J H
Fertil Steril. 1975 Jan;26(1):29-39.
Different types of rigid, reversible, vas deferens occlusive devices were developed and evaluated in 14 unilaterally vasectomized dogs. All prosthetic devices had molded silicone rubber bodies, and rigid inflow and outflow tubes. Various techniques for the removal of the vas luminal epithelium, and for the preparation of porous ceramic and etched stainless steel surfaces to encourage tissue ingrowth into the prosthetic device end tubues were attempted. The devices differed in their methods of achieving occlusion. One device used a "rotary stem valve" which had a C-section rotating mechanism; the others used the "shuttle stem valve" which possessed an occlusive element that moved transverse to the axis of flow in the device, thus occluding the device when the stem was depressed. The rotarystem valve was implanted by means of a longitudinal incision. The remaining 13 shuttle stem devices were placed in the vas using either a longitudinal or a transverse implantation. Inno case was sperm transport through the prosthetic devices obtained for more than a few ejaculations.
在14只单侧输精管结扎的犬中开发并评估了不同类型的刚性、可逆性输精管阻塞装置。所有假体装置都有模制硅橡胶主体以及刚性的流入和流出管。尝试了各种去除输精管腔上皮的技术，以及制备多孔陶瓷和蚀刻不锈钢表面以促进组织向内生长到假体装置末端小管中的方法。这些装置在实现阻塞的方法上有所不同。一种装置使用具有C形截面旋转机构的“旋转杆阀”；其他装置使用“穿梭杆阀”，其具有一个阻塞元件，该元件在装置中垂直于流动轴移动，因此当杆被压下时会阻塞装置。旋转杆阀通过纵向切口植入。其余13个穿梭杆装置通过纵向或横向植入放置在输精管中。在任何情况下，通过假体装置的精子运输都不会超过几次射精。
