Albà M M, Lee D, Pearl F M, Shepherd A J, Martin N, Orengo C A, Kellam P
Wohl Virion Centre, Department of Immunology and Molecular Pathology, Windeyer Institute of Medical Sciences, University College London, London, UK.
Nucleic Acids Res. 2001 Jan 1;29(1):133-6. doi: 10.1093/nar/29.1.133.
VIDA is a new virus database that organizes open reading frames (ORFs) from partial and complete genomic sequences from animal viruses. Currently VIDA includes all sequences from GenBank for Herpesviridae, Coronaviridae and Arteriviridae. The ORFs are organized into homologous protein families, which are identified on the basis of sequence similarity relationships. Conserved sequence regions of potential functional importance are identified and can be retrieved as sequence alignments. We use a controlled taxonomical and functional classification for all the proteins and protein families in the database. When available, protein structures that are related to the families have also been included. The database is available for online search and sequence information retrieval at http://www.biochem.ucl.ac.uk/bsm/virus_database/ VIDA.html.
VIDA是一个新的病毒数据库，它整理了来自动物病毒的部分和完整基因组序列中的开放阅读框（ORF）。目前，VIDA包含了来自GenBank的疱疹病毒科、冠状病毒科和动脉炎病毒科的所有序列。这些开放阅读框被组织成同源蛋白家族，这些家族是根据序列相似性关系确定的。识别出潜在功能重要性的保守序列区域，并可作为序列比对检索出来。我们对数据库中的所有蛋白质和蛋白质家族使用了受控的分类学和功能分类。如果有相关的蛋白质结构，也会将其纳入其中。该数据库可在http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html上进行在线搜索和序列信息检索。
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