Anyanwu A C, McGuire A, Rogers C A, Murday A J
The UK Cardiothoracic Transplant Audit, Clinical Effectiveness Unit, The Royal College of Surgeons of England, London, UK.
Thorax. 2001 Mar;56(3):218-22. doi: 10.1136/thorax.56.3.218.
The EuroQol is a generic questionnaire developed to provide a simple method for assigning utility values to health. This study examines the applicability of the EuroQol to the measurement of quality of life in single, bilateral, and heart-lung transplantation.
A cross sectional study was performed in 87 patients awaiting lung transplantation and in 255 transplant recipients attending follow up clinics in four transplant units.
In the waiting list group 61% reported extreme problems in at least one of the five EuroQol quality of life domains compared with 20% single lung recipients, 4% bilateral lung recipients, and 2% heart-lung recipients at 3 or more years after transplantation. The mean utility value of patients on the waiting list was 0.31. In comparison, utility values for recipients 3 years after transplantation were 0.61 for single, 0.82 for bilateral, and 0.87 for heart-lung transplants. The utility scores and health profiles of bilateral and heart-lung recipients were consistently superior to those of single lung recipients. Problems in all five domains were more frequent in single lung recipients. Subjective assessment with a visual analogue scale showed a similar trend.
The EuroQol is a simple method of deriving a single utility value for quality of life and is responsive to changes after lung transplantation. It is worth considering as a means of monitoring quality of life after transplantation and as an index of quality of survival in research studies in solid organ transplantation. These data suggest that quality of life after transplantation of one lung is inferior to that after transplantation of two lungs.
欧洲五维健康量表（EuroQol）是一种通用问卷，旨在提供一种为健康状况赋予效用值的简单方法。本研究探讨了欧洲五维健康量表在单肺移植、双肺移植和心肺移植生活质量测量中的适用性。
对87例等待肺移植的患者以及在四个移植单位的随访门诊就诊的255例移植受者进行了横断面研究。
在等待名单组中，61%的患者报告在欧洲五维健康量表的五个生活质量领域中至少有一个存在极端问题，相比之下，单肺移植受者在移植后3年及以上时这一比例为20%，双肺移植受者为4%，心肺移植受者为2%。等待名单上患者的平均效用值为0.31。相比之下，移植后3年单肺移植受者的效用值为0.61，双肺移植受者为0.82，心肺移植受者为0.87。双肺移植和心肺移植受者的效用得分和健康状况始终优于单肺移植受者。单肺移植受者在所有五个领域的问题都更频繁。视觉模拟量表的主观评估显示了类似的趋势。
欧洲五维健康量表是一种为生活质量得出单一效用值的简单方法，并且对肺移植后的变化有反应。它值得作为监测移植后生活质量的一种手段以及实体器官移植研究中生存质量的一个指标来考虑。这些数据表明，单肺移植后的生活质量低于双肺移植后的生活质量。
