药用食品。XXII. 来自豌豆（Pisum sativum L. 的未成熟种子）的齐墩果烷型三萜寡糖苷、豌豆皂苷I和II以及贝壳杉烷型二萜寡糖苷、豌豆苷A和B的结构

Medicinal foodstuffs. XXII. Structures of oleanane-type triterpene oligoglycosides, pisumsaponins I and II, and kaurane-type diterpene oligoglycosides, pisumosides A and B, from green peas, the immature seeds of Pisum sativum L.

作者信息

Murakami T, Kohno K, Matsuda H, Yoshikawa M

机构信息

Kyoto Pharmaceutical University, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2001 Jan;49(1):73-7. doi: 10.1248/cpb.49.73.

DOI:10.1248/cpb.49.73

PMID:11201229

Abstract

Two new oleanane-type triterpene oligoglycosides, pisumsaponins I and II, and two new kaurane-type diterpene oligoglycosides, pisumosides A and B, were isolated from the immature seeds (green peas) of Pisum sativum L. together with soyasaponin I, bersimoside I, dehydrosoyasaponin I, and their 6'-methyl esters. The structures of pisumsaponins and pisumosides were determined on the basis of chemical and physicochemical evidence as 22-O-malonylsoyasapogenol B 3-O-alpha-L-rhamnopyranosyl(1-->2)-beta-D-galactopyranosyl(1-->2)-beta-D-glucopyranosiduronic acid (22-O-malonylsoyasaponin I), sandosapogenol 3-O-alpha-L-rhamnopyranosyl(1-->2)-beta-D-galactopyranosyl(1-->2)-beta-D-glucopyranosiduronic acid, 17-O-beta-D-glucopyranosyl-6beta,7beta,13gamma,17-tetrahydroxy-19-kauranoic acid 19-O-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranoside, and 6beta,7beta,13beta,17-tetrahydroxy-19-kauranoic acid 19-O-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranoside, respectively.

摘要

从豌豆（Pisum sativum L.）的未成熟种子（嫩豌豆）中分离出两种新的齐墩果烷型三萜寡糖苷，豌豆皂苷I和II，以及两种新的贝壳杉烷型二萜寡糖苷，豌豆苷A和B，同时还分离出大豆皂苷I、贝西莫苷I、脱氢大豆皂苷I及其6'-甲酯。基于化学和物理化学证据确定豌豆皂苷和豌豆苷的结构分别为22-O-丙二酰大豆皂苷元B 3-O-α-L-鼠李吡喃糖基(1→2)-β-D-吡喃半乳糖基(1→2)-β-D-吡喃葡萄糖醛酸苷（22-O-丙二酰大豆皂苷I）、桑多皂苷元3-O-α-L-鼠李吡喃糖基(1→2)-β-D-吡喃半乳糖基(1→2)-β-D-吡喃葡萄糖醛酸苷、17-O-β-D-吡喃葡萄糖基-6β,7β,13γ,17-四羟基-19-贝壳杉烷酸19-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷，以及6β,7β,13β,17-四羟基-19-贝壳杉烷酸19-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷。