Whitelaw A, Rosengren L, Blennow M
Division of Child Health, University of Bristol, Bristol, UK.
Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F90-1. doi: 10.1136/fn.84.2.f90.
Median neurofilament and glial fibrillary acidic protein concentrations in the cerebrospinal fluid of 18 infants with posthaemorrhagic ventricular dilatation were 20-200 times higher than control values. S-100 protein in cerebrospinal fluid was four times higher than control values. Glial fibrillary acidic protein concentrations correlated with death or disability and with parenchymal lesions but not with shunt dependence.
18例出血后脑室扩张婴儿脑脊液中的神经丝蛋白和胶质纤维酸性蛋白浓度中位数比对照值高20 - 200倍。脑脊液中的S - 100蛋白比对照值高4倍。胶质纤维酸性蛋白浓度与死亡或残疾以及脑实质病变相关,但与分流依赖无关。