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脑出血后心室扩张中的脑特异性蛋白质。

Brain specific proteins in posthaemorrhagic ventricular dilatation.

作者信息

Whitelaw A, Rosengren L, Blennow M

机构信息

Division of Child Health, University of Bristol, Bristol, UK.

出版信息

Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F90-1. doi: 10.1136/fn.84.2.f90.

DOI:10.1136/fn.84.2.f90
PMID:11207222
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1721221/
Abstract

Median neurofilament and glial fibrillary acidic protein concentrations in the cerebrospinal fluid of 18 infants with posthaemorrhagic ventricular dilatation were 20-200 times higher than control values. S-100 protein in cerebrospinal fluid was four times higher than control values. Glial fibrillary acidic protein concentrations correlated with death or disability and with parenchymal lesions but not with shunt dependence.

摘要

18例出血后脑室扩张婴儿脑脊液中的神经丝蛋白和胶质纤维酸性蛋白浓度中位数比对照值高20 - 200倍。脑脊液中的S - 100蛋白比对照值高4倍。胶质纤维酸性蛋白浓度与死亡或残疾以及脑实质病变相关,但与分流依赖无关。

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本文引用的文献

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Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF.患有肌萎缩侧索硬化症和其他神经退行性疾病的患者脑脊液中的神经丝蛋白水平会升高。
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