Morita M, Wang H L
Department of Preventive Dentistry, Okayama University Dental School, Japan.
J Periodontol. 2001 Jan;72(1):79-84. doi: 10.1902/jop.2001.72.1.79.
The relationship between oral malodor and sulfide levels in periodontal pockets (pS) has not yet been determined. The aims of this study were: 1) to identify the correlation among oral malodor, pS levels, and the BANA (benzoyl-DL-arginine-naphthylamide) test and 2) to recognize the interaction between oral malodor, demographic factors, tongue coating, and periodontal condition.
Eighty-one periodontal patients participated in this study. A portable sulfide monitor and organoleptic method were used to evaluate oral malodor. Demographic data included age, gender, race, and smoking habits. The volume of tongue coating and periodontal condition for all teeth were assessed. The pS levels of 3 different radiographic bone loss (RBL) sites: RBL < 2 mm, healthy; RBL > or = 2 to < 4 mm; low to moderate; RBL > or = 4 mm, severe, were measured using an industrial sulcular sulfide-monitoring device. Subgingival plaque samples from the above 3 sites and tongue scraping were examined by the BANA test.
The volume of tongue coating (P<0.001), extent of periodontal disease (P<0.05), pS levels of the sites with low to moderate bone loss (P<0.05), and BANA score of tongue scrapings (P<0.05) were significantly associated with oral malodor. Stepwise multiple regression analysis examined the degree of association between oral malodor and potential explanatory variables. The volume of tongue coating and percent of sites BOP (bleeding on probing) were significantly associated with oral malodor. Females and smoking habit were negatively correlated with organoleptic measurements.
The pS level of the representative sites with low to moderate bone loss demonstrated a modest association with oral malodor. Oral malodor in periodontal patients was primarily associated with tongue coating and gingival inflammation.
口腔异味与牙周袋内硫化物水平（pS）之间的关系尚未明确。本研究的目的是：1）确定口腔异味、pS水平与BANA（苯甲酰-DL-精氨酸-萘酰胺）试验之间的相关性；2）认识口腔异味、人口统计学因素、舌苔与牙周状况之间的相互作用。
81名牙周病患者参与了本研究。使用便携式硫化物监测仪和感官评估法评估口腔异味。人口统计学数据包括年龄、性别、种族和吸烟习惯。评估舌苔量和所有牙齿的牙周状况。使用工业用龈沟硫化物监测装置测量3个不同放射学骨丧失（RBL）部位的pS水平：RBL<2mm，健康；RBL≥2至<4mm，低至中度；RBL≥4mm，重度。通过BANA试验检查上述3个部位的龈下菌斑样本和舌刮样本。
舌苔量（P<0.001）、牙周疾病程度（P<0.05）、低至中度骨丧失部位的pS水平（P<0.05）以及舌刮样本的BANA评分（P<0.05）与口腔异味显著相关。逐步多元回归分析检验了口腔异味与潜在解释变量之间的关联程度。舌苔量和探诊出血（BOP）部位百分比与口腔异味显著相关。女性和吸烟习惯与感官评估测量结果呈负相关。
低至中度骨丧失代表性部位的pS水平与口腔异味呈适度关联。牙周病患者的口腔异味主要与舌苔和牙龈炎症相关。
