De Boever E H, De Uzeda M, Loesche W J
Department of Biological and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor.
J Clin Dent. 1994;4(4):114-9.
The aim of this study was to obtain measurements of oral malodor, as measured by volatile sulfur compounds (VSC), in periodontally healthy individuals without any complaints of bad breath, and to compare the results with data obtained from patients with complaints of oral malodor. The quality of the mouth air was assessed organoleptically and a portable sulfide monitor was used to measure the concentration of VSC in mouth air. The gingival health of 35 individuals (21 M, 14 F; ages 18-57 years) without any malodor complaints was evaluated according to the Papillary Bleeding Score (PBS). Pocket depths and Bleeding upon Probing (BOP) were also recorded in 20 patients (11 females and 9 males ranging in age from 14 to 71 years) who complained of oral malodor. Scrapings of the dorsal surface of the tongue and each of 6 plaque samples per patient were evaluated for the presence of BANA-positive species, such as T. denticola, P. gingivalis, and B. forsythus. The organoleptic ratings and VSC values were significantly higher in the complaint group (p < 0.05). Subjects in the complaint group had a significantly higher percentage of bleeding sites (p < 0.005) and had significantly more plaques that tested positive for the presence of BANA-hydrolyzing species (p < 0.05). Tongue scrapings of subjects with a high organoleptic score consistently yielded a positive BANA reaction suggesting that the dorsal surface of the tongue is an important niche for BANA-positive, VSC-producing bacteria. This study suggests that the primary sources of VSC production are BANA-hydrolyzing bacteria in the plaque and on the dorsal surface of the tongue.
本研究的目的是对无口臭主诉的牙周健康个体进行挥发性硫化物（VSC）测量的口腔异味检测，并将结果与有口腔异味主诉患者的数据进行比较。通过感官评估口腔空气的质量，并使用便携式硫化物监测仪测量口腔空气中VSC的浓度。根据乳头出血评分（PBS）对35名无任何异味主诉的个体（21名男性，14名女性；年龄18 - 57岁）的牙龈健康状况进行评估。还记录了20名主诉有口腔异味的患者（11名女性和9名男性，年龄14至71岁）的牙周袋深度和探诊出血（BOP）情况。对每位患者的舌背刮片和6个菌斑样本分别进行评估，以检测是否存在BANA阳性菌，如齿垢密螺旋体、牙龈卟啉单胞菌和福赛坦氏菌。主诉组的感官评分和VSC值显著更高（p < 0.05）。主诉组的出血部位百分比显著更高（p < 0.005），且检测出BANA水解菌阳性的菌斑显著更多（p < 0.05）。感官评分高的受试者的舌刮片 consistently yielded a positive BANA reaction表明舌背是BANA阳性、产生VSC细菌的重要生态位。本研究表明，VSC产生的主要来源是菌斑和舌背表面的BANA水解菌。 （注：“consistently yielded a positive BANA reaction”这里翻译得不是很准确，因为“consistently”这个词在这里不好准确对应翻译，大致意思是一直产生阳性BANA反应，但可能需要结合更准确的语境来调整）
