母亲吸烟与早期断奶风险：一项荟萃分析。
Maternal smoking and the risk of early weaning: a meta-analysis.
作者信息
Horta B L, Kramer M S, Platt R W
机构信息
Department of Social Medicine, School of Medicine and Psychology, Universidade Católica de Pelotas, Pelotas, Brazil.
出版信息
Am J Public Health. 2001 Feb;91(2):304-7. doi: 10.2105/ajph.91.2.304.
Abstract
OBJECTIVES
This study reviewed evidence on the effect of maternal smoking on early weaning.
METHODS
The following databases and journals were searched: Medline, Scientific Citation Index, Pediatrics, Journal of Pediatrics, New England Journal of Medicine, and Lancet. Analysis was restricted to studies in which infants who had never been breastfed were excluded or the prevalence of breastfeeding initiation was more than 90%.
RESULTS
In smoking vs nonsmoking mothers, the random effects odds ratio for weaning before 3 months was 1.93 (95% confidence interval [CI] = 1.55, 2.40). An adjusted odds ratio of 1.50 (95% CI = 1.34, 1.68) was shown in studies that had lost-to-follow-up rates below 15% and included adequate adjustment for confounding.
CONCLUSIONS
Maternal smoking increases the risk of early weaning.
摘要
目的
本研究回顾了关于母亲吸烟对早期断奶影响的证据。
方法
检索了以下数据库和期刊：医学索引数据库（Medline）、科学引文索引（Scientific Citation Index）、《儿科学》（Pediatrics）、《儿科学杂志》（Journal of Pediatrics）、《新英格兰医学杂志》（New England Journal of Medicine）和《柳叶刀》（Lancet）。分析仅限于排除了从未进行母乳喂养婴儿的研究，或母乳喂养起始率超过90%的研究。
结果
在吸烟母亲与不吸烟母亲中，3个月前断奶的随机效应比值比为1.93（95%置信区间[CI]=1.55, 2.40）。在失访率低于15%且对混杂因素进行了充分调整的研究中，调整后的比值比为1.50（95%CI = 1.34, 1.68）。
结论
母亲吸烟会增加早期断奶的风险。
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