新生羔羊的血浆促红细胞生成素
Plasma erythropoietin in newborn lambs.
作者信息
Sjaastad O V, Egeli A K, Blom A K, Framstad T
机构信息
Department of Biochemistry, Physiology and Nutrition, The Norwegian School of Veterinary Science, Oslo.
出版信息
Acta Vet Scand. 2000;41(4):381-5. doi: 10.1186/BF03549628.
In the present study early postnatal changes in erythropoietin (Epo) level and hemoglobin concentration in 8 lambs were examined. Plasma Epo was estimated by a monoclonal enzyme-immunoassay (ELISA), developed for human Epo. In all the lambs, except one, Epo was low, or undetectable, immediately after birth. Within 6-12 h after birth, a marked increase in plasma Epo was found in 4 of the lambs. Within 3-7 days after birth, Epo was back to low levels. In the lamb with high Epo levels at birth, drastic decreases were observed during the next 6 h. There was no obvious correlation between the hemoglobin concentrations and the changes in plasma Epo.
在本研究中，对8只羔羊出生后早期促红细胞生成素（Epo）水平和血红蛋白浓度的变化进行了检测。血浆Epo采用针对人Epo开发的单克隆酶免疫测定法（ELISA）进行评估。除一只羔羊外，所有羔羊出生后即刻Epo水平较低或无法检测到。出生后6 - 12小时内，4只羔羊的血浆Epo显著升高。出生后3 - 7天内，Epo又回到低水平。出生时Epo水平高的羔羊，在接下来的6小时内观察到急剧下降。血红蛋白浓度与血浆Epo的变化之间没有明显的相关性。
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