Osakabe N, Baba S, Yasuda A, Iwamoto T, Kamiyama M, Takizawa T, Itakura H, Kondo K
Functional Food Research and Development Laboratory, Meiji Seika Kaisha Ltd., Chiyoda Sakado, Japan.
Free Radic Res. 2001 Jan;34(1):93-9. doi: 10.1080/10715760100300091.
Nine male volunteers were given 36 g of cocoa powder (containing 2610 mg of polyphenols) per day with sugar and 6 volunteers received an equivalent amount of sugar for 2 weeks. Conjugated diene production in LDL induced by 2-2' azobis(4-methoxy-2,4-dimethylvaleronitrile) (V-70) and copper ion were evaluated. The lag time was significantly prolonged at 1 and 2 weeks in V-70 and at 2 weeks in copper ion after cocoa powder consumption. The level of excretion of epicatechin in urine was significantly higher in the cocoa group than that in the control group. In conclusion, the antioxidants in cocoa powder might be absorbed and increase the resistance of human LDL to oxidation.
九名男性志愿者每天摄入36克可可粉（含2610毫克多酚）并加糖，六名志愿者连续两周摄入等量的糖。评估了2-2'偶氮二（4-甲氧基-2,4-二甲基戊腈）（V-70）和铜离子诱导的低密度脂蛋白（LDL）中共轭二烯的生成。食用可可粉后，V-70组在第1周和第2周以及铜离子组在第2周时，延迟时间显著延长。可可组尿中表儿茶素的排泄水平显著高于对照组。总之，可可粉中的抗氧化剂可能被吸收并增加人体低密度脂蛋白对氧化的抵抗力。
