Holzner B, Kemmler G, Kopp M, Moschen R, Schweigkofler H, Dünser M, Margreiter R, Fleischhacker W W, Sperner-Unterweger B
Department of Biological Psychiatry, Innsbruck University Hospital, Austria.
Psychosomatics. 2001 Mar-Apr;42(2):117-23. doi: 10.1176/appi.psy.42.2.117.
In a study of breast cancer survivors, the authors used the European Organization for Research and Treatment of Cancer core questionnaire + breast module (EORTC QLQ-C30/+BR23) and the Functional Assessment of Cancer Therapy-Breast (FACT-B)for the assessment of quality of life (QoL). The main focus of this study was to look at the effect of time elapsed since initial treatment on the patients' QoL. Eighty-seven female patients (average age of 53.9 +/- 8.7 years) were included in the study. All women had received curative cancer therapy. The average time elapsed since start of initial treatment was 4.7 +/- 4.3 years. Reduced QoL, especially in the areas of emotional, social, and sexual functioning, was found not only after initial treatment (1-2 years) but also after long posttreatment survival (> 5 years). From these findings, needs for specific psycho-oncological interventions are derived. The findings imply that besides recovering from the acute consequences of cancer therapy, long-term survivors of breast cancer (> 5 years after initial treatment) still may have a special need for psycho-oncological support.
在一项针对乳腺癌幸存者的研究中，作者使用了欧洲癌症研究与治疗组织核心问卷+乳腺模块（EORTC QLQ-C30/+BR23）以及癌症治疗功能评估-乳腺（FACT-B）来评估生活质量（QoL）。本研究的主要重点是观察自初始治疗以来所经过的时间对患者生活质量的影响。87名女性患者（平均年龄53.9±8.7岁）被纳入该研究。所有女性均接受了根治性癌症治疗。自初始治疗开始以来所经过的平均时间为4.7±4.3年。研究发现，生活质量下降，尤其是在情感、社交和性功能方面，不仅在初始治疗后（1至2年）出现，而且在长期治疗后存活期（>5年）也出现。从这些发现中得出了对特定心理肿瘤学干预措施的需求。这些发现意味着，除了从癌症治疗的急性后果中恢复过来之外，乳腺癌长期幸存者（初始治疗后>5年）可能仍然特别需要心理肿瘤学支持。
