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吗啡对暴露于应激状态大鼠脑内组胺水平的影响。

Effect of morphine on the brain histamine levels in stress-exposed rats.

作者信息

Eroğlu L

出版信息

Psychopharmacology (Berl). 1979 May 8;63(1):13-5. doi: 10.1007/BF00426914.

DOI:10.1007/BF00426914
PMID:112615
Abstract

The effect of morphine on brain histamine levels in stress-exposed rats was investigated. It seemed that the brain histamine level was not directly affected by stressors. However, morphine induced a sharp rise in the brain histamine levels in both morphine-treated and morphine-treated stressed groups. This effect of morphine was reversed by naloxone.

摘要

研究了吗啡对遭受应激的大鼠脑内组胺水平的影响。应激源似乎并未直接影响脑内组胺水平。然而，吗啡使接受吗啡治疗组和接受吗啡治疗的应激组大鼠的脑内组胺水平急剧升高。吗啡的这一作用可被纳洛酮逆转。

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引用本文的文献

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Antagonistic action of naloxone on central histamine receptors-stimulated corticosterone secretion in rats under stress.纳洛酮对处于应激状态下大鼠中枢组胺受体刺激的皮质酮分泌的拮抗作用。

本文引用的文献

1
A method for the fluorometric assay of histamine in tissues.一种用于组织中组胺荧光测定的方法。
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Possible role of brain histamine in morphine addiction.
Life Sci. 1975 Jul 1;17(1):55-6. doi: 10.1016/0024-3205(75)90234-9.
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10
Histamine as a transmitter in brain.组胺作为脑内的一种神经递质。
Life Sci. 1975 Aug 15;17(4):503-17. doi: 10.1016/0024-3205(75)90083-1.