Wennerholm W B
Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital, Ostra, Göteborg, Sweden.
Hum Reprod. 2000 Dec;15 Suppl 5:18-25. doi: 10.1093/humrep/15.suppl_5.18.
This paper provides an overview of the effects of cryopreservation on obstetric outcome and child development. Cryopreservation of embryos has no apparent negative impact on perinatal outcome and early infant development. The available data do not indicate an elevated congenital malformation rate. Intracytoplasmic sperm injection and cryopreservation is comparable with conventional in-vitro fertilization and cryopreservation. It remains unclear if embryo freezing poses long-term risks to children so conceived. There are several potential advantages of oocyte freezing which, however, is still a research procedure.
本文概述了冷冻保存对产科结局和儿童发育的影响。胚胎冷冻保存对围产期结局和婴儿早期发育没有明显负面影响。现有数据未表明先天性畸形率升高。卵胞浆内单精子注射与冷冻保存与传统体外受精及冷冻保存相当。尚不清楚胚胎冷冻是否会给由此孕育的儿童带来长期风险。卵母细胞冷冻有几个潜在优势，不过它仍是一种研究性操作。
