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Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.使用微孔板Alamar蓝分析法对临床结核分枝杆菌分离株进行快速、低技术含量的最低抑菌浓度测定。
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秘鲁利马女性患者的医院感染控制与耐多药肺结核

Hospital control and multidrug-resistant pulmonary tuberculosis in female patients, Lima, Peru.

作者信息

Willingham F F, Schmitz T L, Contreras M, Kalangi S E, Vivar A M, Caviedes L, Schiantarelli E, Neumann P M, Bern C, Gilman R H

机构信息

University of Maryland, School of Medicine, Baltimore, Maryland, USA.

出版信息

Emerg Infect Dis. 2001 Jan-Feb;7(1):123-7. doi: 10.3201/eid0701.010117.

DOI:10.3201/eid0701.010117
PMID:11266302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2631673/
Abstract

We examined the prevalence of tuberculosis (TB), rate of multidrug-resistant (MDR) TB, and characteristics of TB on a female general medicine ward in Peru. Of 250 patients, 40 (16%) were positive by sputum culture and 27 (11%) by smear, and 8 (3%) had MDRTB. Thirteen (33%) of 40 culture-positive patients had not been suspected of having TB on admission. Six (46%) of 13 patients whose TB was unsuspected on admission had MDRTB, compared with 2 (7%) of 27 suspected cases (p = 0.009). Five (63%) of 8 MDRTB patients were smear positive and therefore highly infective. In developing countries, hospital control, a simple method of reducing the spread of MDRTB, is neglected.

摘要

我们调查了秘鲁一家女性综合内科病房的结核病(TB)患病率、耐多药结核病(MDR-TB)发病率以及结核病特征。在250名患者中,40人(16%)痰培养呈阳性,27人(11%)涂片呈阳性,8人(3%)患有耐多药结核病。40名培养阳性患者中有13人(33%)入院时未被怀疑患有结核病。入院时未被怀疑患有结核病的13名患者中有6人(46%)患有耐多药结核病,而27名疑似病例中有2人(7%)患有耐多药结核病(p = 0.009)。8名耐多药结核病患者中有5人(63%)涂片呈阳性,因此具有高度传染性。在发展中国家,医院防控这一减少耐多药结核病传播的简单方法被忽视了。